Kaitlyn Abe @kaitlynabe.bsky.social · 16/07/20264/5: We've also explanded from two to six LEA proteins. All six protected Polα-primase from AWI damage but each produced a unique orientation distribution suggesting that AWI protection is a shared property while orientation control is LEA-specific. 100 0
Kaitlyn Abe @kaitlynabe.bsky.social · 16/07/20265/5: Combining datasets collected with different LEA proteins computationally produced more isotropic reconstructions. Surprisingly, premixing multiple LEA proteins before grid preparation did not simply combine their effects and produced unexpected orientation distributions. 020 0
