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Tove Harris @toveharris.bsky.social · 12/01/2026

1/5 Virenpersistenz bei durch Coronaviren ausgelöste Katzenkrankheit - #LongCOVID Forscher der UC Davis entdeckten, dass das für die Katzeninfektiöse Peritonitis (FIP) verantwortliche Katzen-Coronavirus ein viel breiteres Spektrum an Immunzellen infiziert als bisher angenommen. #COVID #COVID19

Scientific Frontline: "At a Glance" Summary
• Main Discovery: Researchers at UC Davis discovered that the feline coronavirus responsible for Feline Infectious Peritonitis (FIP) infects a much broader range of immune cells than previously believed, including B and T lymphocytes, rather than being limited to a single cell type.
• Methodology: The team examined lymph node samples from cats with naturally occurring FIP, analyzing the presence of viral material and evidence of active viral replication within specific immune cell populations.
• Mechanism: The study confirmed that the virus actively replicates inside these critical immune cells—B lymphocytes (antibody producers) and T lymphocytes (infection fighters)—instead of merely leaving behind inert fragments.
• Key Finding: Traces of the virus were found to persist in immune cells even after antiviral treatment was concluded and the cats appeared clinically healthy, suggesting a mechanism for disease relapse or long-term immune disruption.
• Implication: Because some immune cells have multi-year lifespans, this persistence offers a valuable model for understanding human long COVID and chronic post-viral syndromes, providing a rare opportunity to study viral reservoirs in immune tissues inaccessible in human patients.

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Tove Harris @toveharris.bsky.social · 12/01/2026

Zur Studie: "Beyond macrophages: FIPV tropism includes T and B lymphocytes" www.sciencedirect.com/science/arti...

sciencedirect.com

Beyond macrophages: FIPV tropism includes T and B lymphocytes

If untreated, feline infectious peritonitis (FIP) is a fatal disease that is caused by feline infectious peritonitis virus (FIPV), a virulent biotype …

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Tove Harris @toveharris.bsky.social · 12/01/2026

2/5 Darunter B- und T-Lymphozyten. Das Katzen-Coronavirus sei somit nicht auf einen einzigen Zelltyp beschränkt. Die Studie bestätige, dass sich das Virus aktiv in diesen wichtigen Immunzellen – B-Lymphozyten und T-Lymphozyten – vermehre. #Coronaviren #COVID #COVID19 #LongCOVID

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