SBGrid's eLife paper received a citation in July from Eric Fischer from @danafarber.bsky.social in @science.org: Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues.
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Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
Lysine acetyltransferases (KATs) cooperate with oncogenes such as c-Myc, estrogen receptor, and lysine methyltransferase 2A (KMT2A) fusions to sustain malignant programs. Targeting of KAT proteins…