Roger Struble, MD, MPH @jazzscrubs.bsky.social · 02/12/2024First, the basics: 3,608 patients, 74 hospitals, 7 countries, 9 years. This wasn’t a quick study—it was a global, multicenter marathon to settle the “7 vs. 14 days” debate for bloodstream infections. 🏥🌍 100
Roger Struble, MD, MPH @jazzscrubs.bsky.social · 02/12/2024The numbers: Mortality: 14.5% (7 days) vs. 16.1% (14 days) C. diff rates? Same. No harm detected in most subgroups, though confidence intervals were wide in some (e.g., gram-positive infections, high frailty scores). 🤔 100
Roger Struble, MD, MPH @jazzscrubs.bsky.social · 02/12/2024Before you start ordering 7-day courses for everyone, here’s the fine print: Staph aureus? Excluded. Indwelling devices? Excluded. Severely immunocompromised? Yep, excluded. This is for gram-negative bacteremia without major complications. Keep your judgment hat on. 🧠👨⚕️ 110
