Leptospirosis, caused by pathogenic Leptospira spp. such as L. interrogans, is a bacterial zoonosis of increasing prevalence with no consistently effective treatments in severe cases. We sought to ...

Cystic echinococcosis (CE), a neglected zoonotic disease caused by Echinococcus granulosus sensu lato, remains a significant public health and veterinary concern worldwide. Despite efforts to devel...

Published in The Pediatric infectious disease journal

Forested Guinea has been the site of multiple high-consequence viral spillover events, including the index case of the 2013-16 West African Ebola epidemic. Deforestation and wildlife hunting rapidl...

Thelazia callipaeda is an emerging zoonotic eyeworm that infects the ocular tissues of domestic and wild mammals, including humans. This study describes the first molecularly confirmed pediatric ca...

Rift Valley fever virus (RVFV), Crimean-Congo hemorrhagic fever virus (CCHFV), and several zoonotic flaviviruses represent an emerging threat to animal and human health. In Algeria, particularly in...

The Quadripartite One Health Joint Plan of Action and the WHO's Pandemic Agreement emphasise operationalising the One Health (OH) approach to strengthen global preparedness, prevention and response...

To map the available evidence on human cases of New World screwworm across the Americas and identify guidance relevant to surveillance and management.

Toxoplasma gondii is a widespread zoonotic parasite that can infect nearly all warm-blooded vertebrates. Wild boars (Sus scrofa) are valuable indicator hosts because of their broad habitat use, omn...

Rabies remains a major public health problem in resource-limited countries, particularly in sub-Saharan Africa. The objective of this study was to assess the knowledge, attitudes, and practices (KA...

Giardia duodenalis is a flagellated commensal protozoan that can infect both humans and animals. Infection can result in clinical signs such as diarrhea or, more often, the infection can be subclin...

In hyperendemic settings, a reduction in notification curves may reflect that surveillance capacity is deteriorating rather than indicating epidemiological improvement; this distinction has direct ...

Fasciolosis caused by Fasciola hepatica is an economically important parasitic disease of livestock and a major zoonotic disease in humans. Vaccination is a promising strategy to reduce the impact ...

The oral cavity provides a suitable environment for various microorganisms, including protozoa such as trichomonads, which may be associated with periodontal disease development. Humans are conside...

Brucellosis is a widespread zoonosis caused by Gram-negative Brucella coccobacilli. Renal involvement, particularly acute kidney injury (AKI), is uncommon. A 47-year-old construction worker with li...

Climate and land use change are reshaping the dynamics of vector-borne diseases. West Nile virus (WNV), the most widespread zoonotic arbovirus in the United States, illustrates the need to integrat...

Francisella tularensis is a highly virulent, gram-negative bacterial pathogen that causes the zoonotic disease tularemia. F. tularensis infects a variety of host cells and replicates intracellularl...

Zoonotic and environmentally driven health threats increasingly emerge at the human-animal-environment interface, highlighting the need for prevention-oriented and community-centered One Health app...

Toxocara canis infection is a neglected zoonosis associated with multisystemic involvement and persistent larval infection. Murine models are widely used to investigate host-parasite interactions, ...

Intensive farming, wildlife trade, and close human-animal contact in traditional markets for food (TMFs) are widely considered drivers of zoonotic disease emergence. However, comparative evidence a...

Coxiella burnetii is endemic in Great Britain dairy herds but detailed investigations of C. burnetii epidemiology and impacts on livestock production in this region are scarce. The objectives of th...

Hemorrhagic fever with renal syndrome (HFRS) and leptospirosis are environmentally associated zoonoses in China, yet their long-term temporal dynamics and predictive determinants have not been syst...

Cryptosporidium spp. are enteric protozoan parasites of public health importance, particularly in low-resource settings where humans, animals and environmental water sources frequently interact. Th...

To assess whether mandatory notification adequately captures recorded human leishmaniasis in Central Tuscany, Italy, by describing source-specific trends during 2014-2024 and evaluating notificatio...

Mastomys natalensis is a widespread rodent species in sub-Saharan Africa and is increasingly recognised as an important component of food systems in some communities. However, rodents may harbour g...

Bovine brucellosis is a major zoonotic disease in Pakistan, yet diagnostic tests used in national surveillance have never been validated under field conditions. This cross-sectional study estimated...

Chlamydia psittaci (Cps) causes psittacosis, a zoonotic disease characterized by severe pneumonia and systemic infection, yet its pathogenic mechanisms remain poorly understood. While plasmids are ...

Ebola Virus Disease (EVD) is a zoonosis caused by Orthoebolavirus zairense (EBOV). Outbreaks of EVD have occurred in the Democratic Republic of Congo (DRC), and an Expanded Access Program (EAP) wit...

Bovine leptospirosis is a zoonosis of global importance that is associated with reproductive losses. Although diagnosis in females has advanced, genital infection in males remains poorly understood...

Foodborne hepatitis E is an emerging zoonosis in Europe, with domestic pigs recognized as the main reservoir of zoonotic hepatitis E virus (HEV) genotype 3. This study evaluated HEV circulation in ...

Middle East respiratory syndrome (MERS), caused by MERS coronavirus (MERS-CoV), is a zoonotic disease transmitted from camels-to-humans. We applied a targeted rapid research needs appraisal (RRNA) ...

Q fever, caused by Coxiella burnetii, is a globally distributed zoonosis associated with small ruminants. In Mediterranean regions, where extensive farming systems prevail, understanding environmen...

Toxoplasmosis is a zoonosis widespread worldwide, although it primarily affects populations in underdeveloped countries. In humans, infection can lead to serious complications, particularly in immu...

Mechanistic frameworks linking climate to zoonotic disease risk through host ecology remain rare, limiting transferable insights across systems. We develop a Bayesian framework combining an integra...

Paragonimiasis, a food-borne zoonosis caused by Paragonimus spp., can cause severe pulmonary inflammation and fibrosis. However, relationships among the host, parasite and lung microbiome at define...

Mathematical models of plague dynamics provide insight into zoonotic transmission processes and epidemic persistence but often neglect stochastic effects and seasonal variability. In this study, we...

Climate change is reshaping pastoralist mobility across Somalia, creating overlooked pathways for zoonotic disease emergence. Recurrent droughts, floods, and environmental degradation force livesto...

Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is an underrecognized zoonotic disease in sub-Saharan Africa affecting health, food security, and livelihoods. In Benin, research mainly de...

Within the One Health framework applied to global health issues including antimicrobial resistance (AMR) and zoonoses, ecological linkages between animals, wastes, soil, water, and humans are incre...

Cryptosporidium is responsible not only for large economic losses in the livestock sector, but also for high mortality in infants and immunocompromised people all over the world. Although multiple ...

The emergence of zoonotic diseases is increasingly recognized as a critical global health threat, especially in rural Southeast Asia experiencing rapid socio-demographic and environmental changes. ...

Emerging infectious diseases are a hallmark of the Anthropocene1,2. Human-driven ecosystem changes and human-wildlife-livestock contact can drive the emergence of zoonotic and vector-borne diseases...

Trypanosoma lewisi is a flagellated hemoprotozoan that primarily infects rats (Rattus spp.), with Xenopsylla cheopis acting as its cyclical vector. Although typically host-specific, occasional zoon...

Hantaviruses are a diverse and widespread group of zoonotic viruses under the Orthohantavirus genus that can cause severe acute cardiopulmonary or renal disease. Hantavirus species are grouped gene...

West Nile virus (WNV) is a vector-borne zoonotic pathogen maintained in a bird-mosquito cycle, occasionally infecting humans and horses. It is considered a re-emerging pathogen in Europe, with recu...

Glanders (malleus), a highly contagious zoonotic disease caused by Burkholderia mallei, remains an important transboundary disease of equids despite extensive control efforts in many countries. How...

Sporotrichosis, a subcutaneous mycosis caused by Sporothrix spp., has emerged as a major zoonotic disease in Brazil, primarily driven by Sporothrix brasiliensis. The southern state of Rio Grande do...

The present study provides the first comprehensive evaluation of Toxoplasma gondii and Neospora caninum infections in Iraqi animals and birds. Data from 116 Iraqi studies were subjected to various ...

Hantaviruses are globally distributed reservoir-associated viruses that cause haemorrhagic fever with renal syndrome (HFRS), mainly in Eurasia, and hantavirus cardiopulmonary syndrome (HCPS; also t...

Pteropine orthoreoviruses are emerging bat-borne zoonotic viruses of the genus Orthoreovirus (family Reoviridae), increasingly recognized as causes of acute respiratory disease in humans. Originall...