Im thrilled to share that our manuscript is online now at Nature.
www.nature.com/articles/s41...
In this study we find novel cross reactivity between commensal specific T cells and host proteins. This highlights mechanisms that influence commensal-induced autoimmunity.
nature.com
Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation - Nature
Dysregulated CD4 T cells that recognize gut commensal antigens are able to infiltrate the central nervous systems and are re-stimulated by host proteins, resulting in neuroinflammation.
