Excited to share our latest work!
The oncogenic m5C writer NSUN2 achieves substrate specificity by recognizing RNA structure and conformational dynamics. RNA folding shapes methylation! Congratulations to the team! Thank you, colleagues and supporters! ttps://nature.com/articles/s41586-026-10582-9
nature.com
Substrate selectivity of the human RNA m5C methyltransferase NSUN2 - Nature
NSUN2 is an enzyme that adds a small chemical mark to RNA molecules and uniquely selects its targets based on specific sequence patterns and structural features.
