Reposted by @yangkl96.bsky.socialBioMassSpec @realbiomassspec.bsky.social · 14/01/2026A New Detailed Mass Offset Search in MSFragger for Improved Interpretation of Complex PTMs #JProteomeRes pubs.acs.org/doi/10.1021/...pubs.acs.orgA New Detailed Mass Offset Search in MSFragger for Improved Interpretation of Complex PTMsConventional database search methods for proteomics struggle when tasked with identifying dozens or hundreds of modifications simultaneously. Open or error-tolerant searches can address this limitatio... 012
yangkl96.bsky.social @yangkl96.bsky.social · 12/11/2025So glad to see this online today! With FragPipe and the many other Koina APIs, we wanted to democratize deep learning, especially for those without access to expensive GPUs. Major kudos to my co first author Ludwig for setting up the server. I encourage ML developers to put their models on Koina 0101
yangkl96.bsky.social @yangkl96.bsky.social · 25/03/2025Yes this was when I was rotating in the lab learning how to use MSFragger! After a Google search, it looks like @proteomicsnews.bsky.social presented a poster at ASMS? 130
yangkl96.bsky.social @yangkl96.bsky.social · 25/03/2025Lots of overlap in PTMs identified by the different groups, like glycosylation. I'm not sure if there was ever an official poster showing the performance of the different software 110
yangkl96.bsky.social @yangkl96.bsky.social · 25/03/2025There was the #ALSMinePTMs challenge back in 2020! Tried to identify differential PTMs in CSF samples from healthy and ALS patients. proteomicsnews.blogspot.com/2020/10/the-...proteomicsnews.blogspot.comThe Winner of the 2020 Data Mineathon Challenge/ #ALSMinePTMs is.....First of all, I can't thank everyone enough for putting up with the chaos that was #ALSMinePTMs. Thank you judges! Thank you random friend... 110
