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Yana Bromberg

@yanabromberg.bsky.social
198 followers 88 following 7 posts

Bioinformatics geek. Prof @Emory, CS and Biology. Learning protein-ish and deciphering the DNA blueprint of life

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Reposted by Yana Bromberg
Nature Methods @natmethods.nature.com · 06/04/2026
A model-agnostic empirical framework measures the uncertainty associated with protein embeddings and assesses their biological relevance to improve model reliability. @yanabromberg.bsky.social www.nature.com/articles/s41...
nature.com
Quantifying uncertainty in protein representations across models and tasks - Nature Methods
A model-agnostic empirical framework is proposed to measure the uncertainty associated with protein embeddings and to assess the biological relevance of these embeddings in order to improve model reli...
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Reposted by Yana Bromberg
Megan Barker @meganbarkerase.bsky.social · 11/06/2025
The slide you submitted | The slide you’re presenting #tcteac #PragueSights
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Reposted by Yana Bromberg
Itai Yanai @itaiyanai.bsky.social · 11/06/2025
Yana Bromberg at the Woodstock Night Science conference #TCTEAC @yanabromberg.bsky.social
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Yana Bromberg @yanabromberg.bsky.social · 12/05/2025
Are you using AI models on protein or DNA sequences? Did you maybe forget that their embeddings come with no obvious measure of reliability? Imagine how sequence analysis would suffer if source sequences were sometimes subtly randomized. This is exactly what happens if we use low-quality embeddings.
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Reposted by Yana Bromberg
Jason McDermott @biodataganache.bsky.social · 06/01/2025
Shout out to Hot Tub concocted papers at #psb2025! Our Ten Simple Rules for Scientific Comics arose from a hot tub hypothesis with @yanabromberg.bsky.social - "Hey, I bet we could write a paper on scientific comics!" @pacsym.bio Do you have any 'hot tub' papers? journals.plos.org/ploscompbiol...
Photo of a slide titled "Hot Tub Hypotheses" - featuring a photo of the conference hot tub and our Ten Simple Rules for Drawing Scientific Comics paper
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Yana Bromberg @yanabromberg.bsky.social · 13/12/2024
This and 'mirror' cells... and we are done www.science.org/doi/10.1126/...
science.org
A synthetic protein-level neural network in mammalian cells
Artificial neural networks provide a powerful paradigm for nonbiological information processing. To understand whether similar principles could enable computation within living cells, we combined de n...
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Reposted by Yana Bromberg
Veera Rajagopal @doctorveera.bsky.social · 12/12/2024
Association of polygenic scores for neuropsychiatric traits with self-reported professions based on analysis of 420k individuals from UK Biobank and Million Veteran Program. Look at the 'arts & design' category. Artistic talent comes at a cost--a piece of your mind :)
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Yana Bromberg @yanabromberg.bsky.social · 12/12/2024
Excited to share our latest work in #metagenome analysis. We built REMME/REBEAN to analyze and label sequencing #reads. End result? We can label activity of #microbiome #proteins with minimal homology to #enzymes we've seen before. Great work by R. Prabakaran! www.biorxiv.org/content/10.1...
biorxiv.org
Deciphering enzymatic potential in metagenomic reads through DNA language model
The microbial world plays a fundamental role in shaping Earth's biosphere, steering global processes such as carbon and nitrogen cycling, soil rejuvenation, and ecological fortification. An overwhelmi...
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