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John Christodouleas

@xristodouleas.bsky.social

Radiation Oncologist at PENN and Elekta Medical Affairs.

John Christodouleas @xristodouleas.bsky.social · 23/06/2025

t.co/BBFJjqLdMS GBM Rad Oncs: if 5 fx is proven non-inferior with respect to OS, does it win the day? As a non-GBM doc, I’m puzzled why in 2025 this hasn’t been already investigated more broadly given the prognosis and prior work from Stanford. @mrlconsortium.bsky.social

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John Christodouleas @xristodouleas.bsky.social · 27/04/2025

@mrlconsortium.bsky.social Early indication of treatment response in rectal cancer using sequential diffusion-weighted imaging on a 1.5 T MR-linac. user-swndwmf.cld.bz/ESTRO-2025-A.... Study from Tübingen suggests ADC changes during 1st week of chemo-RT might be prognostic of treatment response.

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ESTRO 2025 - Abstract Book

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John Christodouleas @xristodouleas.bsky.social · 27/04/2025

@mrlconsortium.bsky.social Outcomes of patients with liver oligometastases treated with MRI- or cone-beam CT-guided SBRT from MOMENTUM and OligoCare registries:

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ESTRO 2025 - Abstract Book

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John Christodouleas @xristodouleas.bsky.social · 27/04/2025

@mrlconsortium.bsky.social Feasibility of Therapist-Driven MR-guided adaptive radiotherapy for oligometastatic disease: user-swndwmf.cld.bz/ESTRO-2025-A... From Princess Margaret Cancer Center. Shows comparable dosimetric outcomes between RTT-led vs. RO-led online adaption for oligo-mets.

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ESTRO 2025 - Abstract Book

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John Christodouleas @xristodouleas.bsky.social · 23/04/2025

The SPRINT and MOMENTUM studies exemplify Common Sense (Radiation) Oncology. As a field, we must reject traditional Pharma-centric RCT models and adopt methodologies better suited to RadOnc. That means: platform registries, TwiCs, and Bayesian designs.

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John Christodouleas @xristodouleas.bsky.social · 16/04/2025

More fodder for the bladder filling debate.

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John Christodouleas @xristodouleas.bsky.social · 16/02/2025

For muscle-invasive bladder cancer, the Lancet Oncology paper by Zlotta et al is the best comparative effectiveness study of TMT versus RC. How can we use this study to communicate the risks of delayed cystectomy to patients? Peppin A et al provide an answer at GU ASCO 2025:

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John Christodouleas @xristodouleas.bsky.social · 05/02/2025

Dan Hyer is a talented communicator. If you have a Unity, don’t miss his presentation on how to optimize use of CMM. If you can’t make it live, a recording will be available afterwards on the Consortium website.

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John Christodouleas @xristodouleas.bsky.social · 06/01/2025

In a future where we adapt (almost) every fraction—regardless of imaging modality—thoughtful and efficient remote access workflows will be essential. Join us and share your best practices!

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Reposted by John Christodouleas

Alison Tree @alison-tree.bsky.social · 20/12/2024

We are looking for a new consultant colleague at The Royal Marsden Sutton. You too could have the joy of working with @ccparker.bsky.social and many other wonderful people. You might even get to meet @asharpmedonc.bsky.social! www.jobs.nhs.uk/candidate/jo...

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Job Advert

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Reposted by John Christodouleas

The OncoAlert Network 🚨 @oncoalert.bsky.social · 16/11/2024

MRI Vs CT Guidance for Stereotactic Body Radiotherapy in #ProstateCancer MIRAGE trial out on European Urology Results suggest that MRI-guided SBRT offers long-term benefits in reducing toxic effects by allowing for more aggressive margin reduction in treatment planning. buff.ly/4fA8VmA

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