Reposted by @xinyimiao.bsky.social
Today, we at the @arbelharpak.bsky.social & @docedge.bsky.social labs are excited to share our updated manuscript for PGSUS, a tool for diagnosing confounding in polygenic scores (PGSs).
biorxiv.org
A Litmus Test for Confounding in Polygenic Scores
Polygenic scores (PGSs) are being rapidly adopted for trait prediction in the clinic and beyond. PGSs are often thought of as capturing the direct genetic effect of one's genotype on one's phenotype. ...
