iiinova — where your digital self keeps evolving

William DeWitt @wsdewitt.github.io · 27/06/2026

Supplementary Movie S4 shows cells responding to a stab wound to the yolk. 🤯 (2/2)

William DeWitt @wsdewitt.github.io · 20/05/2026

Game over, phylogeneticists! New DNA foundation model "Carbon" reconstructs the tree of life. 🙃 huggingface.co/spaces/Huggi...

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William DeWitt @wsdewitt.github.io · 08/08/2025

Sam Altman on ChatGPT5: "A legitimate PhD-level expert in anything"... "it can help you understand your healthcare, and make decisions on your journey."

chatgpt5 thinks a savings account with APY 4.10 will make money faster than a savings account with APY 4.8 or 4.9

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William DeWitt @wsdewitt.github.io · 08/06/2025

I'm stoked to have this long-term and highly collaborative effort out in the wild. We present an experimental evolution system to quantitatively study the rapid evolutionary dynamics of B-cell affinity maturation. These evolutionary mechanisms underpin antibody responses and immune memory formation.

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William DeWitt @wsdewitt.github.io · 21/05/2025

Recasting the perils of phylodynamic non-identifiability as a feature not a bug, we show that a unique forward-equivalent process enables exact and efficient simulation from arbitrarily large populations. With M Celentano, S Prillo, @yun-s-song.bsky.social www.pnas.org/doi/10.1073/pnas.2412978122

A full lineage tree and it's corresponding ascertained tree

Tree conditioned on survival is equal in law to an unconditioned tree with modified parameters

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William DeWitt @wsdewitt.github.io · 11/02/2025

New chalkboard mounted and seasoned! 🤓

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William DeWitt @wsdewitt.github.io · 03/02/2025

Snow on UW's Red Square this morning

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William DeWitt @wsdewitt.github.io · 23/12/2024

First post-surgical pow: Snoqualmie opening day, Tuesday before faculty meeting 😊

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William DeWitt @wsdewitt.github.io · 12/11/2024

The latest from @xkcd.com, Geometriphylogenetics (xkcd.com/3010/), with alt text "there's a maximum likelihood that I'm doing phylogenetics wrong". But this is actually kinda a thing (e.g. doi.org/10.1201/9780...)!

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William DeWitt @wsdewitt.github.io · 05/11/2024

SFI's Monolith Beta in today's snow

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William DeWitt @wsdewitt.github.io · 25/09/2024

Enjoying the view from my office at KITP for the next three weeks... I'm here for #viralimmune24, and am recruiting postdocs etc for my new lab at UW! www.kitp.ucsb.edu/activities/v...

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William DeWitt @wsdewitt.github.io · 26/12/2023

Back on ❄️🌋 after 1-year injury hiatus. #fun

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William DeWitt @wsdewitt.github.io · 03/09/2022

Hi, Sceloporus of Tilden Park

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William DeWitt @wsdewitt.github.io · 07/03/2022

An iridescent head feather display from this Anna's 😍

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William DeWitt @wsdewitt.github.io · 16/01/2022

Anna's hummingbirds, busily buzzing about

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William DeWitt @wsdewitt.github.io · 01/01/2022

I’ve been seeing a lot of plump robins #rowndborb

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William DeWitt @wsdewitt.github.io · 26/12/2021

These spirited snow squalls seem to have died down in Fremont #seattlesnow

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William DeWitt @wsdewitt.github.io · 25/12/2021

I was really needing a restorative full-on powder day with @wlstylr. Wow, I haven’t had this much fun in the snow in almost two years (Mt Hood Ski Bowl). ❄️😛🎄😌

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William DeWitt @wsdewitt.github.io · 24/12/2021

Found a Heady Topper at a North Portland grocery

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William DeWitt @wsdewitt.github.io · 09/12/2021

A brief cloud break reveals Tahoma gleaming on high (@dbacsik for scale). 🌋❤️

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William DeWitt @wsdewitt.github.io · 08/12/2021

So can we submit AI dreamt images as journal cover art now?

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William DeWitt @wsdewitt.github.io · 27/11/2021

Oregonings: Elfin Saddle, moist Fomitopsis, and grilled Matsutake

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William DeWitt @wsdewitt.github.io · 12/10/2021

Proofs are developed for the space of piecewise constant functions, showing that any non-identifiable congruence class can be approximated arbitrarily well using identifiable histories. Results are conjectured to extend to an arbitrary-order spline basis. (2/3)