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Wooyoung Choi

@wooyoungchoi.bsky.social
50 followers 126 following 3 posts

Postdoc Yifan Cheng lab | Cryo-EM | fasn fatty acid synthase | pYC system, PhD in Wei Lű & Juan Du lab | Ion channels CALHM2 cryoEM, Master’s Yigong Shi lab & Nieng Yan lab

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Wooyoung Choi @wooyoungchoi.bsky.social · 21/03/2025
www.pnas.org/doi/10.1073/... As a postdoc in Yifan Cheng’s lab in UCSF, I developed the pYC KI system, a very efficient and cost-effective way to modify cells. It provided the fundamental platform of my published FASN work in Nature.
pnas.org
Efficient tagging of endogenous proteins in human cell lines for structural studies by single-particle cryo-EM | PNAS
CRISPR/Cas9-based genome engineering has revolutionized our ability to manipulate biological systems, particularly in higher organisms. Here, we de...
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Wooyoung Choi @wooyoungchoi.bsky.social · 02/03/2025
I am super excited to share that my work at @yifan_ucsf has just been published in Nature🎉 From developing pYC KI system, it was a long journey to understand endogenous protein dynamics. I appreciate the support from FASN team! 🕺Let's dive into the endogenous & dynamic protein world🏊🏄🚣
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Reposted by Wooyoung Choi
Nature [Unofficial] @nature.com.web.brid.gy · 21/02/2025
nature.com
Structural dynamics of human fatty acid synthase in the condensing cycle
Nature, Published online: 20 February 2025; doi:10.1038/s41586-025-08782-w Structural dynamics of human fatty acid synthase in the condensing cycle
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