Reposted by @wonkj.bsky.social
How confident are you in foundation model cell type annotations? This paper explores foundation model confidence scores and offers recalibrations methods especially in the context patient cohort annotations!
Congrats to Guangzheng Weng and @wonkj.bsky.social
www.biorxiv.org/content/10.6...
biorxiv.org
Cross-domain confidence reliability and remappability of frozen single-cell representations
Single-cell foundation models are increasingly adopted for downstream applications such as cell-type prediction. However, these predictions are often utilized without assessing their reliability, or b...