Reposted by Willie NeiswangerAmeya Godbole @ameyagodbole.bsky.social · 24/10/2025Announcing 🔭Hubble, a suite of open-source LLMs to advance the study of memorization! Pretrained 1B/8B param models, with controlled insertion of texts designed to emulate key memorization risks: copyright (e.g., book passages), privacy (e.g., synthetic biographies), and test set contamination 184
Reposted by Willie NeiswangerShangshang Wang @shangshang-wang.bsky.social · 23/04/2025😃 Want strong LLM reasoning without breaking the bank? We explored just how cost-effectively RL can enhance reasoning using LoRA! [1/9] Introducing Tina: A family of tiny reasoning models with strong performance at low cost, providing an accessible testbed for RL reasoning. 🧵 183
Reposted by Willie NeiswangerShangshang Wang @shangshang-wang.bsky.social · 19/02/2025🔍 Diving deep into LLM reasoning? From OpenAI's o-series to DeepSeek R1, from post-training to test-time compute — we break it down into structured spreadsheets. 🧵 152
Willie Neiswanger @willieneis.bsky.social · 07/01/2025Our paper also contains an in-depth discussion on safety when releasing metagenomic models. Looking for collaborators to build on this with us — please reach out! metagene.ai 060
Willie Neiswanger @willieneis.bsky.social · 07/01/2025We leverage the ecosystem of modern LLM tooling—in tokenization, model architecture, training, infra, etc—for performance and extensibility. METAGENE-1 is standardized & easy to use. Hugging Face: huggingface.co/metagene-ai Github: github.com/metagene-ai 160
Willie Neiswanger @willieneis.bsky.social · 07/01/2025METAGENE-1 shows state-of-the-art results on pathogen detection, metagenomic embedding, and other genomic tasks. We also release new benchmarks for genomic detection and embedding (eg, Gene-MTEB, based on MTEB for LLMs). See our paper for details: arxiv.org/abs/2501.02045 140
Willie Neiswanger @willieneis.bsky.social · 07/01/2025Our data pipeline is: human microbiome > wastewater > metagenomic sequences > tokens > training data. Wastewater provides a rich source of data from tens of thousands of species across the human-adjacent microbiome. In total we pretrain on over 1.5T base pairs of DNA/RNA. 110
Willie Neiswanger @willieneis.bsky.social · 07/01/2025Metagenomic sequencing of wastewater produces vast amounts of data that can capture public health trends at a societal scale. Our goal is to train a model on this data to help in large-scale wastewater monitoring & detection of novel bio threats. 110
Willie Neiswanger @willieneis.bsky.social · 07/01/2025Excited to release METAGENE-1, a 7B parameter metagenomic foundation model, built to aid in pathogen detection & pandemic monitoring. Pretrained on 1.5 trillion base pairs of DNA/RNA sequenced from wastewater. A collab w/ USC, PrimeIntellect, & the Nucleic Acid Observatory. metagene.aimetagene.aiMetagenomic Foundation ModelMetagenomic Foundation Model for Pandemic Monitoring 20391
Reposted by Willie NeiswangerKeenan Crane @keenancrane.bsky.social · 09/12/2024Entropy is one of those formulas that many of us learn, swallow whole, and even use regularly without really understanding. (E.g., where does that “log” come from? Are there other possible formulas?) Yet there's an intuitive & almost inevitable way to arrive at this expression. 22543128
Reposted by Willie NeiswangerBrandon Amos @bdamos.bsky.social · 05/12/2024hi everyone!! let's try this optimal transport again 🙃 232931
Reposted by Willie NeiswangerDrew Berry wehi.tv @drewberry.bsky.social · 04/12/2024Delighted to publish my new molecular animation: DNA Break Repair by Homologous Recombination youtu.be/Xe-83tBcxhsyoutu.beDNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tvYouTube video by WEHImovies 38275114
Reposted by Willie NeiswangerMathurin Massias @mathurinmassias.bsky.social · 27/11/2024Anne Gagneux, Ségolène Martin, @quentinbertrand.bsky.social Remi Emonet and I wrote a tutorial blog post on flow matching: dl.heeere.com/conditional-... with lots of illustrations and intuition! We got this idea after their cool work on improving Plug and Play with FM: arxiv.org/abs/2410.02423 1235299