In a phase 1 trial evaluating intravenous delivery of a next-generation CD3×CD19 bispecific T cell engager in patients with active systemic lupus erythematosus, treatment was well tolerated, and there...

Nature Biotechnology - FDA approves oncolytic virus

Nature Biotechnology - FDA approves oncolytic virus

A positive trial holds promise for treating people with cancer. More research is needed to get effective vaccines to the clinic.

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Moderna’s newly approved vaccine could allow manufacturers to respond more rapidly to changing influenza strains.

Edible bait vaccines made Europe virtually free from rabies. The approach could work against bird flu – if we invest in new vaccines.

Little penguins are flightless and return at night to the same burrow, making it easier to capture and vaccinate them.

Vehicles are less likely to smash into deer on the road where the big cats are on patrol.

In this webinar I will interview Associate Professor Andy Flies from the Menzies Institute for Medical Research, University of Tasmania, […]

The Reagent Collaboration Network (Reclone) seeks to address the global asymmetry in research and development in biotechnology across the Global South through open sharing of biomaterials, protocols a...

On 11–14 March 2026, the Vaccine Innovation Forum World 2026 (VIF World 2026) was held in Shanghai, China.

Rapid growth of wind energy plays a key role in global efforts to reduce carbon emissions, yet public concerns persist about its potential health e...

A biology journal that paid peer reviewers found that the approach cut the time to a first editorial decision by 85% and maintained high-quality reviews.

Women are now at the very center of the global cancer control agenda, but there are major challenges ahead.

Discover the world’s best science and medicine | Nature.com

Discover the world’s best science and medicine | Nature.com

This 5-year follow-up of the double-blinded, placebo-controlled phase 3 DEN-03-IB trial evaluating the efficacy and safety of the Butantan dengue vaccine in participants aged 2–59 years in Brazil foun...

PhD students reflect on how their supervisors made a meaningful difference — from quiet acts of kindness to career-shaping guidance.

Many cancers are linked to two modifiable habits: tobacco smoking and alcohol consumption.

Just 2 months into my Ph.D., I was on the verge of quitting. I felt out of my depth, and my broken English left me struggling to keep up with my colleagues.

Physicists combined human acumen and AI-assisted math to show that a doubted particle interaction is possible after all

Immunopaedia is a free educational platform that teaches immunological concepts through clinical case studies.

Harnessing natural behaviors to vaccinate wild bats reduces zoonotic spillover risk while supporting conservation.

Letter to the Editor

In a mouse model, environmental immunostimulation in early life led to cross-reactive adaptive immune memory and reduced type II immune responses to allergens, indicating a mechanistic relationship be...

Letter to the Editor

Information about the roles of each author of a paper can help to build trust, integrity and responsible research assessment. Coordinated efforts are needed to consolidate progress.

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

An intestinal organoid model recapitulates human microfold (M) cell function and transcriptomic profiling and biochemical assays demonstrate that M cells uptake and present antigens to the immune syst...

An intestinal organoid model recapitulates human microfold (M) cell function and transcriptomic profiling and biochemical assays demonstrate that M cells uptake and present antigens to the immune syst...

The transfer of microbiota and pathogens from wild mice to genetically tractable laboratory mice has been shown to enhance modeling of human immune responses in preclinical studies. However, the long-...

Known for detecting land mines, the rodents could also help detect disease.

Salmon Rickettsial Syndrome (SRS) is an emerging disease in Atlantic s...

Gut plasma cells secrete IgA, which prevents infections, neutralizes toxins, and regulates the gut microbiota. Simons et al. demonstrate that stable IgA production results not from the persistence of ...

IgA antibodies protect mucosal surfaces from foreign antigens. Siniscalco et al. identify germinal center (GC)-independent and GC-derived pathways of gut IgA generation following immunization. Sinisca...

Mattingly et al. use human lung cells to show that virus-specific CD8+ tissue-resident memory T cells trigger epithelial antiviral defenses via IFNγ. This early protective response varies by epithelia...

A strange, contagious cancer is threatening Tasmanian devils, but researchers’ fight is fueling breakthroughs in science, survival, and hope.

Researchers will study the effects of the policy on young people’s mental health, social interactions and political engagement.

All vertebrate adaptive immune systems exhibit distinct lymphocyte lineages. In jawless vertebrates, such as lampreys, T-like cells are thought to ...

All vertebrate adaptive immune systems exhibit distinct lymphocyte lineages. In jawless vertebrates, such as lampreys, T-like cells are thought to ...

Can this model beat the baseline?

In this phase 3 trial, a two-dose Ebola vaccine regimen in healthy pregnant women in Rwanda was found to be safe and immunogenic in women and offspring through passive transfer.