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Wei Chen

@weichen2.bsky.social
82 followers 214 following 15 posts

Eberly Postdoctoral Fellow at Penn State with Scott Showalter. PhD from UCSD. Intrinsically disordered proteins, dynamic protein interactions, NMR, smFRET. Taiwanese

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Reposted by Wei Chen
Wei Chen @weichen2.bsky.social · 27/03/2026
Excited to share our new paper! It was a really enjoyable collaboration with the Keating Lab. onlinelibrary.wiley.com/doi/full/10.... We asked a simple question: Do all crowded environments affect protein phase separation the same way? Short answer: no.
onlinelibrary.wiley.com
Residue‐level mapping of crowding effects on protein phase separation
Protein liquid–liquid phase separation has emerged as a key mechanism in cellular organization. While the crowded environment inside cells is expected to influence this process, how crowding shapes t...
164
Wei Chen @weichen2.bsky.social · 27/03/2026
Excited to share our new paper! It was a really enjoyable collaboration with the Keating Lab. onlinelibrary.wiley.com/doi/full/10.... We asked a simple question: Do all crowded environments affect protein phase separation the same way? Short answer: no.
onlinelibrary.wiley.com
Residue‐level mapping of crowding effects on protein phase separation
Protein liquid–liquid phase separation has emerged as a key mechanism in cellular organization. While the crowded environment inside cells is expected to influence this process, how crowding shapes t...
164
Wei Chen @weichen2.bsky.social · 27/05/2025
Now published! Phosphorylation patterns modulate transient secondary structures of the intrinsically disordered CTD of RNA polymerase II www.sciencedirect.com/science/arti...
sciencedirect.com
Phosphorylation modulates secondary structure of intrinsically disorder regions in RNA polymerase II
The intrinsically disordered C-terminal domain (CTD) of RNA polymerase II contains tandem repeats with the consensus sequence YSPTSPS and coordinates …
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Wei Chen @weichen2.bsky.social · 25/11/2024
Excited to share our new review on recent conceptual breakthroughs in IDPs with the help of NMR! From molecular descriptions to cellular functions of intrinsically disordered protein regions pubs.aip.org/aip/bpr/arti...
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