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Vincent Pascat

@vpascat-biostat.bsky.social

PhD, Statistical Geneticist @ Genomics

Vincent Pascat @vpascat-biostat.bsky.social · 18/02/2026

🚨 Proud to share that our paper on the genetic links between type 2 diabetes (T2D) and hypertension is now published in @natcomms.nature.com! We dissect the genetic relationship between T2D and hypertension and show it is not driven by a single shared pathway. 🧬 (1/N)

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Vincent Pascat @vpascat-biostat.bsky.social · 06/02/2026

Polygenic scores are useful for early detection, but also early prevention! New paper shows people with high genetic risk of T2D have 3x more risk of developing it by age 35. Early detection could trigger lifestyle changes, metformin prescription... doi.org/10.1038/s414...

doi.org

Preventing premature deaths through polygenic risk scores - Nature Communications

Via an integrative modelling approach that combines population and clinical trial data, the authors find that polygenic risk score-based screening would reduce premature mortality across seven commonl...

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