Fight4Hematology

Dr. Curtis is the senior director of diagnostic hematology and director of the Platelet & Neutrophil Immunology Lab.

These findings suggest that the PEA is a promising functional test for HIT laboratory diagnostics based on the relatively high sensitivity; however, further studies are needed to validate its clinical...

Dr. Malarkannan is the Gardetto Chair for Immunology and Immunotherapy and a senior investigator at Versiti Blood Research Institute.

The use of sNK cells in immunotherapy emerges as a potentially effective strategy to target and eliminate the majority of ovarian tumour clones, thereby providing a potential therapeutic opportunity i...

Dr. Mast is the Walter Schroeder Endowed Chair for Blood Research and a senior investigator at Versiti Blood Research Institute.

The Dittel Laboratory investigates cellular and molecular mechanisms involved in the regulation of inflammation, a component of virtually every disease.

In multiple sclerosis (MS) the B cell depleting drug ocrelizumab has shown high efficacy in reducing inflammatory activity. Its mechanism of action is unclear due to B cell subset complexity and unkno...

Dr. Mast is the Walter Schroeder Endowed Chair for Blood Research and a senior investigator at Versiti Blood Research Institute.

Clinical trial design for classical hematologic diseases is difficult because samples sizes are often small and not representative of the disease population. The American Society of Hematology initiat...

Dr. Baumann Kreuziger is a medical director of hematology and investigator at Versiti Blood Research Institute who specializes in non-malignant hematology.

Guidelines for diagnosing pulmonary embolism (PE) start with a risk assessment using a pretest probability (PTP) tool, followed by D-dimer testing or computed tomography pulmonary angiography (CTPA) d...

Tirthadipa Pradhan-Sundd, PhD is an associate investigator at Versiti Blood Research Institute, whose research focuses on Transfusion Medicine, Vascular Biology and Cell Therapy.

Pain constitutes a significant comorbidity associated with sickle cell disease (SCD). Analgesics serve as the primary method for pain management; however, the long-term effects of these drugs on the l...

Dr. Chen is an assistant investigator at Versiti Blood Research Institute, whose research focuses on atherosclerosis and its underlying mechanisms.

Angiotensin 1-7 and a TERT activator individually restore vasodilatory capacity within the microcirculation previous SARS-CoV-2 infection

Joshua Muia, PhD is an associate investigator at Versiti Blood Research Institute, whose research focuses on structural and functional studies of ADAMTS13, vascular biology, and coronary artery diseas...

These results demonstrate the crucial role of arginine methylation on ADAMTS13 secretion and activity. Our findings may shed new light on the mechanism of allosteric regulation of ADAMTS13, which may ...

Senior Investigator Emeritus Thomas Abshire, MD, studied the evaluation of mild bleeding disorders and clinical trials in Von Willebrand disease (VWD).

These findings support durability of the Kids-DOTT randomized clinical trial findings of net clinical benefit at 2 years.

Dr. Mast is the Walter Schroeder Endowed Chair for Blood Research and a senior investigator at Versiti Blood Research Institute.

The effectiveness of concizumab is mediated through the blockade of TFPI anticoagulant activities in plasma and on multiple physiological surfaces. An important and previously unrecognized function of...

Dr. Zhu is an investigator at Versiti Blood Research Institute who focuses on understanding cell surface receptors and how they transmit signals.

<span><i>Borrelia burgdorferi</i> exists in a complex enzootic life cycle requiring differential gene regulation. P66, a porin and adhesin, is upregulated and essential during mammalian infection, but...

Dr. Baumann Kreuziger is a medical director of hematology and investigator at Versiti Blood Research Institute who specializes in non-malignant hematology.

Not available.

The Dittel Laboratory investigates cellular and molecular mechanisms involved in the regulation of inflammation, a component of virtually every disease.

What's on the horizon?

Dr. Baumann Kreuziger is a medical director of hematology and investigator at Versiti Blood Research Institute who specializes in non-malignant hematology.

Immune thrombotic thrombocytopenic purpura (iTTP) is a chronically relapsing disorder caused by autoantibody-mediated deficiency of ADAMTS13. Rituximab is frequently administered to prevent relapses, ...

Dr. Anderson will now lead the organization's Medical Sciences Institute (MSI), providing strategic leadership and guiding innovative research and clinical programs.

NCML mismatching is present in HLA-matched unrelated HCT donor and recipient pairs and may contribute to outcomes in unrelated HLA-matched HCT.

The Qizhen Shi, MD, PhD, laboratory at Versiti Blood Research Institute studies gene and cell therapies for treatment of hemophilia A and hemophilia B.

Platelet-Targeted Gene Therapy for Hemophilia A with Inhibitor History