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Jianhan Chen

@umassmdlab.bsky.social
244 followers 90 following 1 posts

Professor at UMass Amherst; computational biophysics: intrinsically disordered proteins, ion channels, protein nanopores, biomolecular condensates, multi-scale RNA and protein modeling, enhanced sampling

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Jianhan Chen @umassmdlab.bsky.social · 03/12/2024
Excited to share our new coarse grained model of dynamic RNA for phase separation simulations. The model is still evolving and any feedback is welcomed! www.biorxiv.org/content/10.1...
biorxiv.org
An Intermediate Resolution Model of RNA Dynamics and Phase Separation with Explicit Mg2+
RNAs are major drivers of phase separation in the formation of biomolecular condensates. Recent studies suggest that RNAs can also undergo protein-free phase separation in the presence of divalent ion...
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