Deb and colleagues identify ENPP1 as a critical negative regulator of kidney regeneration. They demonstrate that targeting ENPP1 using a novel humanized monoclonal antibody enhances tubular cell proli...

Aging is characterized by a decline in the ability of tissue repair and regeneration after injury. In skeletal muscle, this decline is largely driven by impaired function of muscle stem cells (MuSCs) ...

Hao et al. developed a CRISPR-based system that records cell signaling activity as DNA edits readable by imaging, enabling single-cell reconstruction of signal strength and revealing long-lasting memo...

The potential use of in vitro gametogenesis (IVG) as a reproductive technology could redefine parentage, including the possibility of bipaternal parentage, raising hopes for those who have infertility...

An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

Funded entirely by taxpayer dollars, this first-of-its-kind drug targets cellular metabolism to promote tissue repair of multiple organs.

Mammalian primordial germ cells (PGCs) are embryonic precursors to the adult germline and must facilitate high-fidelity transfer of genomic material f…

Wamaitha and colleagues used the rhesus macaque to characterize the transcriptional and spatial mechanisms underlying ovarian reserve formation in prenatal life providing insights into the molecular p...

As developmental biologists, we tell origin stories to explain differences in vertebrate craniofacial form and complexity. Some of these differences a…

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

The system, developed by UCLA and UC Berkeley scientists, could be used to help ensure global food security by increasing crop yields.

The team, led by Andrew Goldstein, was awarded $1 million to identify metabolic pathways that drive tumor growth in the liver and explore whether targeting these pathways could enhance patient surviva...

UCLA Molecular, Cell and Developmental Biology | 14 followers on LinkedIn. The Department of Molecular, Cell, and Developmental Biology advances our knowledge of life on earth at the cellular and mole...