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UCI Center for the Study of Cannabis

@ucicannabis.bsky.social
51 followers 10 following 92 posts

University of California Irvine School of Medicine's Center for the Study of Cannabis: cannabis.uci.edu

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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 05/10/2026
🎙️ ICAL Director Dr. Daniele Piomelli joins the Neurology Podcast to discuss marijuana rescheduling and what it means for the future of neurological research and care. Don't miss it! 🧠🌿 🎧 Available now on Spotify: open.spotify.com/episode/58xE... #Cannabis #Neurology #ICAL #CannabisResearch
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 28/09/2026
New publication from ICAL director Dr. Daniele Piomelli in Neuropsychopharmacology! 🧠 Pain and stress aren't separate experiences — they're one unified biological response. The endocannabinoid system plays a key role in controlling this pain–stress axis. Read → doi.org/10.1038/s413...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 14/09/2026
📢 Call for papers: Cannabis & Cannabinoid Research special issue on minor cannabinoids (CBG, CBN, THCV, CBDV, acidic + semisynthetic compounds). Mechanisms, PK, product chemistry, clinical safety, policy. Deadline April 30, 2027. Select the special issue in ScholarOne. 🧪
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 07/09/2026
📣 Cannabis researchers! UCI ICAL Tissue Bank: adolescent Δ9-THC–exposed rodent brain + peripheral tissue. FREE (accredited institutions) | No DEA license Shipping covered by requester Limited supply. DM for details. #CannabisResearch #THC
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 31/08/2026
🧠 Liking cannabis ≠ wanting cannabis. This commentary from ICAL's Dr. Daniele Piomelli explores the neurobiology behind what actually drives cannabis use — and why it matters as policy evolves. 📄 jpet.aspetjournals.org/article/S002... #CannabisScience #Neuroscience #AddictionResearch"
jpet.aspetjournals.org
Liking isn’t enough: You got to want it
The regulatory landscape for cannabis and cannabinoid-based therapeutics is shifting, most recently marked by the US Drug Enforcement Agency’s recommendation to reclassify cannabis from Schedule I to…
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 26/08/2026
🎙️ Why does pain become chronic for some people and not others? New Science at the Source: We talk with Natalia Malek, PhD (Wroclaw University of Science and Technology in Poland) about CB2 receptors, microglia, and whether cannabinoids could stop pain before it sticks around. youtu.be/qBrY78IDazs
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 24/08/2026
🎙️ Why does pain become chronic for some people and not others? New Science at the Source: We talk with Natalia Malek, PhD (Wroclaw University of Science and Technology in Poland) about CB2 receptors, microglia, and whether cannabinoids could stop pain before it sticks around. youtu.be/qBrY78IDazs
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 17/08/2026
📢 Re-upping from ICAL: THC for sickle cell pain? 🧬 In a humanized mouse model of SCD, acute THC eased mechanical and cold pain sensitivity, with no memory or anxiety cost. Tolerance crept in for cold with repeated dosing. A possible opioid alternative. DOI: 10.1124/jpet.124.002285
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 10/08/2026
📌 Cannabinerds, mark your calendars! ICRS 2027 is going to Banff. 🏔️ 🗓️ July 4–8, 2027 · Banff, Alberta, Canada 37th Annual Symposium on the Cannabinoids. See you in the Rockies. icrs.com #ICRS2027 #Cannabinoids #CannabinoidScience
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 03/08/2026
🔁 Re-upping a favorite. In "Science at the Source" Ep. 7, I talk with Dr. Christine Gall (UC Irvine) on how teen THC reshapes memory circuits, and why females may be more vulnerable. Still holds up. 🎥 www.youtube.com/watch?v=iBdV... #CannabisResearch #Neuroscience
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 27/07/2026
Millions of people use cannabis for chronic pain. But why does it work — and does the science actually back it up? Dr. Daniele Piomelli from UCI's Center for the Study of Cannabis just answered that question in detail. Watch on YouTube: ▶️ www.youtube.com/watch?v=A7T1...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 20/07/2026
📢 Cannabis researchers! The UCI ICAL Tissue Bank offers adolescent Δ9-THC-exposed tissue—brain & organs, male/female rodents, flash-frozen or fixed.🌟 FREE, worldwide 🛡️ No DEA Schedule-I license needed—great for pilot data Brain tissue in high demand! DM us 🌱🔗 @ucicannabis
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 13/07/2026
🌟 Science at the Source is back! Dr. Hilary Marusak sits down with world-renowned cannabinoid researcher Dr. Daniele Piomelli to talk endocannabinoids, brain health & the future of cannabis research. 🧠🌿 👉 www.youtube.com/watch?v=Px45... #CannabinoidResearch #Neuroscience
youtube.com
Exploring the Science of Cannabinoids with Dr. Daniele Piomelli | Science at the Source Ep. 1
Welcome to the debut episode of Science at the Source! 🎥 In this series, we take you straight to the heart of groundbreaking research, interviewing students and scientists at the UC Irvine Center…
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 06/07/2026
🚨 Rewind to Science at the Source Ep. 5 Dr. Steve Mahler breaks down the neuroscience of craving, THC, and motivation—and what it means for cannabis use and addiction treatment. Still thinking about this one. 🎥 www.youtube.com/watch?v=9ImB... IG → @uci_cannabis #CannabisResearch #Motivation
youtube.com
Exploring Motivation, Cannabinoids, and the Brain with Dr. Steve Mahler| Science at the Source Ep. 5
Welcome back to Science at the Source! 🎙️ In this episode, we sit down with Dr. Steve Mahler, neuroscientist and Professor at UC Irvine, to explore how the brain’s motivation and reward systems are…
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 29/06/2026
Hot take: the brain's immune system might hold the key to understanding addiction. 🔥 I sat down with Maricela Martinez (@uci_cannabis) to talk microglia, adolescent vulnerability, and the science of early drug exposure. Check out this awesome episode: 🎧 www.youtube.com/watch?v=koYL...
youtube.com
Microglia in Addiction & Early Career Development w/ Marcielo Martinez | Science at the Source Ep. 6
Welcome back to Science at the Source! 🎙️ In this episode, we sit down with Maricela Martinez, PhD student and rising star in neuroimmunology, to explore the groundbreaking connections between…
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 22/06/2026
🧠 Turns out microglia—the brain's immune cells—are key partners in memory. In this UC Irvine ICAL study, depleting them disrupted endocannabinoid-dependent plasticity and episodic memory; boosting 2-AG signaling rescued both. 🔗 www.jneurosci.org/content/45/2... #Neuroscience #Microglia
jneurosci.org
Microglia Support Both the Singular Form of LTP Expressed by the Lateral Perforant Path and Episodic Memory
We report here that microglia exert a surprisingly discrete but functionally critical influence on synaptic plasticity in the mouse hippocampus. Treatment of adult male mice with colony-stimulating…
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 15/06/2026
🌿 Is cannabis a psychedelic? Dr. Daniele Piomelli (UC Irvine, ICAL) breaks down how cannabinoids compare to traditional psychedelics—and what it means for brain health. 🧠 📽️ Watch (20 min): youtu.be/G0tagjX8COw #CannabisScience #Neuroscience #Psychedelics #Cannabinoids
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 01/06/2026
🧠 Liking cannabis ≠ wanting cannabis. This commentary from ICAL's Dr. Daniele Piomelli explores the neurobiology behind what actually drives cannabis use — and why it matters as policy evolves. 📄 jpet.aspetjournals.org/article/S002... #CannabisScience #Neuroscience #AddictionResearch
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 25/05/2026
Honoring those who gave their lives in service to our country. Wishing everyone a meaningful Memorial Day. 🇺🇸 — UCI ICAL
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 18/05/2026
🔁 Resharing a must-listen episode of Science at the Source 🎙️ Hilary Marusak talks with Rodrigo M. Klein, PhD, Postdoctoral Scholar in the Piomelli Lab at UC Irvine. Breaks down how THC exposure influences neurodevelopment from fetal life through adolescence. 🎧 www.youtube.com/watch?v=oap6...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 13/05/2026
🔬 Researchers: UCI ICAL Tissue Bank is offering free adolescent THC exposure specimens — brain and peripheral tissues from exposed mice/rats. ✔ Free worldwide ✔ No DEA license needed ✔ Perfect for pilot data ⚠️ Brain tissue limited. First-come, first-served. Request now: @uci_cannabis #Cannabis #THC
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 04/05/2026
Big thanks to our UCI ICAL Advisory Group for a fantastic meeting! 🙌 Grateful for the expertise and guidance of Ken Mackie, Allyn Howlett, Marisa Roberto, and Yasmin Hurd. Your insights are shaping the future of cannabinoid research. #ICAL #UCI #CannabisScience
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 27/04/2026
🌱 The 36th Annual ICRS Symposium is headed to Dijon, France 🇫🇷 — June 28–July 2, 2026! A can't-miss for cannabinoid and endocannabinoid researchers at every stage. Registration and abstracts are open! icrs.com/annual-icrs-symposium 🌿 #ICRS2026 #cannabinoidresearch
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 20/04/2026
🌿 Just in time for 4/20 — FREE adolescent Δ9-THC exposure specimens available to qualified researchers worldwide. No DEA license required. Brain tissue is limited, so reach out now for inventory & availability! #420 #CannabisScience #THC #NeuroscienceResearch
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 13/04/2026
🎙️ In case you missed it — Ep. 8 of Science at the Source is worth a listen! Dr. Olufunke Ajeigbe on global science, cannabis & brain health, and navigating an impact-driven research career. 🌍🔬 ▶️ /@ucicenterforthestudyofcann5100 #ScienceAtTheSource #TranslationalScience #AcademicCareers
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 06/04/2026
Free THC exposure specimens for cannabinoid researchers. 🔬 UCI ICAL Tissue Bank offers brain & peripheral tissues from adolescent mice/rats — no DEA license required. ⚠️ Brain tissue is limited. Reach out now. 🌿 📸 @uci_cannabis | 🔗 @ucicannabis | 🔗 @ucicannabis.bsky.social #CannabisScience #THC
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 30/03/2026
🌿 Save the date. ICRS 2026 Annual Symposium → Dijon, France June 28–July 2 The world's top cannabinoid science minds, all in one room. Details dropping soon. #cannabinoidresearch #ICRS2026
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 24/03/2026
What do immune cells have to do with memory? More than we thought. UC Irvine's ICAL (Piomelli, Lynch & Gall labs) finds microglia regulate an endocannabinoid pathway critical for memory — and restoring it rescues memory deficits. Chavez et al., 2025. 🔗 www.jneurosci.org/content/45/2... #Neuroscience
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 16/03/2026
The brain has its own immune system—and it may hold the key to addiction. 🧬 Dr. Hilary Marusak & neuroimmunologist Maricela Martinez break down how microglia shape the teenage brain and what drugs like THC & opioids do to them. 🎥 Science at the Source Ep. 6: www.youtube.com/watch?v=koYL...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 09/03/2026
Millions use cannabis for chronic pain — but does the science back it up? Dr. Daniele Piomelli from UCI's Center for the Study of Cannabis breaks it down. 🌿 ▶️ www.youtube.com/watch?v=A7T1... @uci_cannabis (IG) | @ucicannabis.bsky.social (Bluesky) #CannabisResearch #ChronicPain #THC #Pain
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 02/03/2026
📣 Cannabis researchers! UCI ICAL Tissue Bank: adolescent Δ9-THC–exposed rodent brain + peripheral tissue. FREE (accredited institutions) | No DEA license Shipping covered by requester Limited supply. DM for details. #CannabisResearch #THC
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 23/02/2026
🎙️ Science at the Source (Ep. 8) Olufunke Ajeigbe, PhD (UC Irvine) on translational science, global training & academic pathways. 🎧 Watch: /@ucicenterforthestudyofcann5100 #ScienceAtTheSource #UCIrvine
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 16/02/2026
🌿🧠 Can cannabis help manage chronic pain? Dr. Daniele Piomelli explains how THC works through cannabinoid receptors—and what the science actually says. 📺 Watch: www.youtube.com/watch?v=A7T1... #CannabisResearch #ChronicPain #THC #EndocannabinoidSystem #Neuroscience
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 09/02/2026
🌿 Is cannabis a psychedelic? Dr. Daniele Piomelli breaks it down in a crisp 20-min talk—what counts as a psychedelic, how cannabinoids compare, and why it matters for mental health & neuroscience. 🎥 Watch: youtu.be/G0tagjX8COw #CannabisScience #Neuroscience #Psychedelics #EndocannabinoidSystem
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 02/02/2026
New resource for cannabis & cannabinoid researchers! The Resource Center for Cannabis & Cannabinoid Research (R3CR) is a new hub helping scientists navigate regulations, access high-quality materials, and build strong proposals. Led by experts from UM, USP & WSU. More: r3cr.org | LinkedIn @R3CR
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 19/01/2026
📢 Cannabis & cannabinoid researchers: The UCI ICAL Tissue Bank offers FREE adolescent Δ9-THC tissue (brain + peripheral organs) from male & female rodents. Flash-frozen or fixed. No DEA license needed. Brain tissue limited—first come! 📩 Contact us @ucicannabis
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 12/01/2026
From ICAL — excited to share two 2025 publications on adolescent THC exposure and its effects on the brain and body: 📄 J Vis Exp — THC in adolescent & adult mice (Jung KM et al.) 📄 Toxicol Sci — Adolescent THC impairs testicular function (Lim J et al., Jung KM) Congrats to all involved! 🧠✨ #UCI
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 05/01/2026
Big congrats to Steve Mahler’s group at UCI ICAL! 🎉 Their team published 3 major papers in 2025 — including one featured on the cover of the Journal of Neuroimmunology — advancing research on cannabinoids, addiction, and brain–immune interactions. Proud of this amazing work! 🧠✨
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 01/01/2026
🎆 Happy New Year! Wishing you a bright, bold, and brilliant 2026 from all of us at UC Irvine’s ICAL! ✨ Excited to see what new discoveries in cannabis science await us!
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 25/12/2025
🎉 Happy Holidays! From all of us at UC Irvine's ICAL, wishing you joy, rest, and a bright start to 2026! ✨
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 22/12/2025
🚨 Must-watch: Dr. Steve Mahler on how cannabinoids shape motivation, reward, and craving—and why it matters for addiction science. 🎥 www.youtube.com/watch?v=9ImB... @uci_cannabis #Neuroscience #AddictionResearch #Endocannabinoids
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 15/12/2025
📢 Researchers: UCI ICAL Tissue Bank has adolescent Δ9-THC mouse/rat brain & organ samples! 🧠👩🔬❄️ FREE for accredited labs, no DEA license needed. First-come, first-served! 📸 IG: @uci_cannabis | 🔗 X: @ucicannabis #CannabisResearch #THCResearch #Neuroscience
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 08/12/2025
Coming back to this fantastic conversation with ICAL Director Dr. Daniele Piomelli — from the endocannabinoid system to where cannabis science is headed next. A great intro to the science behind cannabinoids. 🎥 www.youtube.com/watch?v=Px45...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 01/12/2025
🚨 Re-upping a fan favorite: Dr. Hilary Marusak + Dr. Christine M. Gall on cannabis, memory, adolescent development, and sex differences in the brain. 🎥 Watch here: www.youtube.com/watch?v=iBdV... Follow: @uci_cannabis #ScienceAtTheSource #Neuroscience #THC #Memory #AdolescentBrain
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 24/11/2025
🔁 Resharing this powerful episode! Dr. Hilary Marusak talks with Dr. Rodrigo Klein (UC Irvine) about how THC shapes the developing brain—from fetal stages to adolescence. 👉 Watch: www.youtube.com/watch?v=oap6...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 17/11/2025
🚨 Microglia & addiction? In Science at the Source Ep. 6, Dr. Hilary Marusak chats with Maricela Martinez on how the brain’s immune cells shape adolescent circuits—and what THC, nicotine, & opioids do. 🧠🌿💡 Watch: www.youtube.com/watch?v=koYL... #Neuroimmunology #Addiction #AdolescentBrain #Microglia
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 10/11/2025
🚨 Researchers: Need adolescent THC tissue? The UCI ICAL Tissue Bank offers brain & organs from THC-treated rodents—flash-frozen or perfused. FREE for accredited labs. No DEA license needed. First-come, first-served! 📩 DM for availability & protocols 🌱🔬 #CannabisResearch #THC #TissueBank #Science
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 03/11/2025
New ICAL paper in J. Neurosci! Microglia support endocannabinoid-dependent LTP and episodic memory. Microglia depletion disrupted LTP and memory in mice—effects reversed by enhancing 2-AG signaling. 📄 Chavez et al., 2025 🔗 www.jneurosci.org/content/45/2...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 27/10/2025
New commentary from ICAL Director Dr. Daniele Piomelli in JPET: “Liking isn’t enough: You got to want it.” As cannabis moves toward Schedule III, Piomelli explores the neurobiology of motivation, abuse liability, and what drives use beyond enjoyment. 🔗 jpet.aspetjournals.org/article/S002...
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UCI Center for the Study of Cannabis @ucicannabis.bsky.social · 13/10/2025
🧠 THC researchers: Get free adolescent THC brain & organ tissue from UCI ICAL Tissue Bank! No DEA license needed, shipping covered. Limited supply—first-come, first-served! 🌱🔬 📩 DM for info IG: @uci_cannabis | X: @ucicannabis REQUEST HERE: cannabis.uci.edu/ical/tissueb... #CannabisResearch #THC
cannabis.uci.edu
ICAL Tissue Bank - UCI Center for the Study of Cannabis
ICAL Tissue Bank ICAL maintains a biobank of brain and peripheral organs collected from mice and rats treated in adolescence with D9-tetrahydrocannabinol (THC) or vehicle. Both male and female…
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