iiinova — where your digital self keeps evolving

Brett Phinney @ucdproteomics.bsky.social · 30/09/2026

This was from one of my Claude code sessions today .

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Brett Phinney @ucdproteomics.bsky.social · 05/09/2026

I really wonder if I’m the only one google Dreambeans sends stuff like this to 🤣https://labs.google/dreambeans

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Brett Phinney @ucdproteomics.bsky.social · 31/08/2026

Today in useless data: I don't know why I was curious about my labs "popular @evosep.bsky.social locations are" But here you go . I apparently need to use S5 more

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Brett Phinney @ucdproteomics.bsky.social · 10/06/2026

My daughter (now a 2nd year grad student at Irvine) found this yesterday. She made it in 1st grade for a school project. Stick around until the last page you won't be sorry 🤣😂

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Brett Phinney @ucdproteomics.bsky.social · 18/05/2026

It's that time of year again for are Annual proteomics chart course! Going on almost 20 years! Honestly it's a good class for those wanting to add proteomics to your research. And Proteomics really is the best Omics if I don't say so myself #proteomics #massspec #proteome #massspectrometry

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Brett Phinney @ucdproteomics.bsky.social · 14/05/2026

I seem to have acquired and kept over 233K mass spec files over there years. Here is a breakdown

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Brett Phinney @ucdproteomics.bsky.social · 13/05/2026

See I Knew I would have some use for keeping every qc file I ever created 😁 I'll have more in a day or two

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Brett Phinney @ucdproteomics.bsky.social · 11/05/2026

Well, I apparently saved over 32K BSA QC files from my LTQ era. Now I need to figure out what to do with them lol

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Brett Phinney @ucdproteomics.bsky.social · 18/03/2026

This is truly hilarious , and accurate !

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Brett Phinney @ucdproteomics.bsky.social · 17/02/2026

Contemplating this as my facilities new logo. What do you think?

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Brett Phinney @ucdproteomics.bsky.social · 27/01/2026

Want to make your DIA-NN QC reports in a web browser and then go back in time to the 80's and 90's? Now you can with my completely AI vibe coded streamline app! dia-nn-qc.streamlit.app You're welcome 😜

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Brett Phinney @ucdproteomics.bsky.social · 26/01/2026

Last minute Candlelight vigil in Davis last night for Alex Pretti organized by Indivisible Yolo. It was a good turnout

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Brett Phinney @ucdproteomics.bsky.social · 14/01/2026

I asked if it made it up. Apparently no.

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Brett Phinney @ucdproteomics.bsky.social · 14/01/2026

I made a google notebook llm based on this www.nature.com/articles/s41... and new data concerning mRNA - Protein expression correlation over the last year. It even wrote a grant , which you can find in there if anyone wants to submit it ! notebooklm.google.com/notebook/2c7...

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Brett Phinney @ucdproteomics.bsky.social · 08/01/2026

I've been having weird issues getting access to Journals here on campus. I think I have narrowed it down to Safari. Has anyone else had this issue? left is Chrome and one the Right is Safari . chatGPT gave me a log list of things to try, but nothing has worked yet. Anyone solve this?

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Brett Phinney @ucdproteomics.bsky.social · 08/01/2026

For the Local UC Davis peeps . Maybe someday we will discuss the illusive beer paper @benneely.com :(

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Brett Phinney @ucdproteomics.bsky.social · 05/01/2026

This was ours, although it's unclear what is causing this . It is likely the opentrons flex we use to load the tips. Whatever it is, it makes the system totally unusable

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Brett Phinney @ucdproteomics.bsky.social · 11/12/2025

I don't know exactly what this all means, but I'm running cascadia github.com/Noble-Lab/ca... on my genome centers A100 80GB GPU so it's probably really cool I'm guessing

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Brett Phinney @ucdproteomics.bsky.social · 02/12/2025

This is our loading buffer on our Exploris 480 /U3000 system today. Coming to Nature Methods ASAP: The Proteomics S.P.I.D.E.R. Method (Suitability Protocol Integrating Dead Eight-legged Reference)

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Brett Phinney @ucdproteomics.bsky.social · 07/11/2025

After all this time , Finally have the evotip loading protocol working on the #Opentrons Flex, so far so good ! @evosep.bsky.social

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Brett Phinney @ucdproteomics.bsky.social · 05/11/2025

Thinking about putting this sign outside my facilities door . 🤔

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Brett Phinney @ucdproteomics.bsky.social · 29/10/2025

My curiosity got the best of me and I searched Grokipedia (Musks AI Wikipedia alternative ) for proteomics . My lord 🙄

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Brett Phinney @ucdproteomics.bsky.social · 06/10/2025

Going through trying my hardest not to delete my old data. Found some ABRF RG data from 2009 and 2011. Doesn't look like we did very good. Wonder if we are any better now?

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Brett Phinney @ucdproteomics.bsky.social · 04/09/2025

Thanks to everyone that attended our #proteomics Short course last week ! We generated over 150 GB of timsTOF HT data comparing different proteomics sample Prep methods .

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Brett Phinney @ucdproteomics.bsky.social · 08/08/2025

What the heck ? Found this in the lab today. What old instrument could this possibly be for?

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Brett Phinney @ucdproteomics.bsky.social · 08/08/2025

I thought this was super interesting. re-analyzed a DIA data file I originally processed with encyclopedia in 2018 with Spectronat 20. Encyclopedia really held up! At least on the protein level. Peptides are more difficult to compare. Surprised me

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Brett Phinney @ucdproteomics.bsky.social · 29/07/2025

Excellent work!! I just love the term Mini-Bulk so I had chatGPT help me whip something up

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Brett Phinney @ucdproteomics.bsky.social · 14/07/2025

This is hilarious , how have I never noticed this before . I suppose if you don’t open the box/tubes = very inefficient

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Brett Phinney @ucdproteomics.bsky.social · 04/07/2025

I'm really liking the new Spectronaut 20 search engine, seems to do a a really good job with unspecific digests. These are examples of chymotrypsin and elastase digests that I searched with no enzyme specificity. Seems to work well!

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Brett Phinney @ucdproteomics.bsky.social · 02/07/2025

Here is one that we had made at the tech Foundry here at UC Davis. It's an adaptor for using the 96 channel Gilson plate master to load evotips @evosep.bsky.social #proteomics www.thingiverse.com/thing:7081394

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Brett Phinney @ucdproteomics.bsky.social · 19/06/2025

I was worried about the cores finances, but now that we identified this protein in a sample, I think we will be okay right? www.uniprot.org/uniprotkb/A0...

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Brett Phinney @ucdproteomics.bsky.social · 18/06/2025

People use the manual Gipson plate master next to it these days . Maybe I’ll use that instead 🤔

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Brett Phinney @ucdproteomics.bsky.social · 10/06/2025

It's that time of year again! Good news this year, we were able to lower prices for those at UC. Come get schooled and learn some cutting edge proteomics! It's fun I promise!! #proteomics #lcms #teammassspec #blueskyscience #DIA

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Brett Phinney @ucdproteomics.bsky.social · 06/06/2025

Sometimes I like to find pictures in our PCA analysis. I see a guy with sunglasses 😎

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Brett Phinney @ucdproteomics.bsky.social · 12/05/2025

Protip , don’t wrap your plates in parafilm and send them on dry ice . It shatters into plastic snow and makes a tremendous mess

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Brett Phinney @ucdproteomics.bsky.social · 06/05/2025

I swear this lyophilizer speed vac combo is one of my favorite things in the lab , it’s so incredibly useful .

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Brett Phinney @ucdproteomics.bsky.social · 24/04/2025

Maybe I shouldn’t have analyzed those Cordyceps samples after all 🤔

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Brett Phinney @ucdproteomics.bsky.social · 24/04/2025

I love coming into campus every morning

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Brett Phinney @ucdproteomics.bsky.social · 23/04/2025

I couldn't get this to work on their main page, had to go to their gemini page 🤣I laughed so hard my work mates probably think i'm nuts

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Brett Phinney @ucdproteomics.bsky.social · 27/03/2025

Parts of this preprint are super cool like this figure. But the use of the Bravo and Astral makes me want to write a preprint entitled "How to consistently commute to work in 3.4 seconds using a McLaren Speedtail and a professional F1 driver"

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Brett Phinney @ucdproteomics.bsky.social · 13/03/2025

This is hilarious , apparently the internet thinks I am smarter and more attractive in an outdoor bathtub compared to using my timsTOF HT in my lab. Plus I am way cuter than they are giving me credit for 🙄

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Brett Phinney @ucdproteomics.bsky.social · 06/03/2025

This is why I don't delete old Mass Spec data. Just 2 years of timsTOF HT data is 16x bigger than all the data I ever acquired on my LTQ-FT (8 plus years?) and the Deca XP+ data is kinda a rounding error

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Brett Phinney @ucdproteomics.bsky.social · 05/03/2025

I think my policy of never deleting anything is not going to be sustainable much longer ....

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Brett Phinney @ucdproteomics.bsky.social · 21/02/2025

Heck Yeah, I just searched over 300 timsTOF HT diaPASEF files with DIA-NN 2.0 on my cluster in under 2 hours. I'll try and make a video of how I did it tomorrow. It's not that terribly hard

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Brett Phinney @ucdproteomics.bsky.social · 13/02/2025

Dry ice cold plunge cryotherapy Anyone ?

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Brett Phinney @ucdproteomics.bsky.social · 01/02/2025

I managed to almost fill my 2TB memory box running 2 fragpipes and 1 sage at once all non-specific with lots of mods !!! Woot!!

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Brett Phinney @ucdproteomics.bsky.social · 31/01/2025

Does anyone know a free alternative that will map peptides ID's on protein sequences the way Peaks does? It's super useful for non-specific peptides

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Brett Phinney @ucdproteomics.bsky.social · 29/01/2025

can't wait to try it! btw I saw this in the docs . I didn't know there were packages like this. Can you recommend one?

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