Reposted by marcélula
Pleased to share that our latest paper is out now in NAR. We demonstrate that Pol η binds to and is a substrate of NEDD8. @ncmoreno.bsky.social @txelah.bsky.social @barneslab.bsky.social @irinabezsonova.bsky.social
academic.oup.com/nar/article/...
academic.oup.com
Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
Abstract. DNA polymerase eta (Pol η) is a Y-family translesion polymerase responsible for synthesizing new DNA across UV-damaged templates. It is recruited