New paper out in @jacs.acspublications.org! We use multiscale methods to reveal how RNA binding allosterically tunes the active site for ATP hydrolysis in a biomolecular motor. 🧬💻 Congrats to Adrián García Martínez and the rest of team!
🔗Check out the full story here:
pubs.acs.org/jacsat/artic...
pubs.acs.org
Tuning the ZIKV NS3
Helicase Motor Activity through
Magnesium Coordination and RNA-Driven Allostery
Abstract. Viral NS3 helicases convert the chemical energy of ATP
hydrolysis
into directional motion along nucleic acids, but the molecular basis
of this co
