The IMPC is pleased to announce the launch of Data Release 24! With this latest release, we are now providing more than 138 million data points to the research community worldwide. This release includes phenotyping data for 9,605 genes from 10,341 mutant lines, adding approximately 4.5 million new data points. The total number of phenotype calls is 111,664 in this release.  As with every release, Data Release 24 not only […]

We conducted a CRISPR screen to identify genes essential for neural differentiation. By integrating these findings with mouse neuroanatomy, we demonstrated its utility in discovering a new PEDS1-related neurodevelopmental disorder.

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The IMPC has significantly impacted the advancement in biomedical research by systematically generating and phenotyping knockout mice for nearly every protein-coding gene. The data IMPC provided has led to major discoveries in gene function, enabled the development of new disease models, and provided an open-access resource that supports translational research and precision medicine.

The IMPC has launched Data Release 23! With this release, we’re now providing more than 100 million data points. This release features phenotyping data for 9,277 genes from 9,994 mutant lines, adding ...

We’re delighted to announce the upcoming 2025 Virtual IMPC conference:“International Mouse Phenotyping Consortium: Insights from the Past, Shaping the Future”! The virtual conference will take place o...