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Tridib Mahata

@tridibmahata.bsky.social

Assistant Professor, NISER, India. Bacterial and phage genetics. Bacterial immune systems and phage encoded anti-microbials.

Posts Replies Media

Reposted by Tridib Mahata

Nature @nature.com · 02/04/2026

Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies. go.nature.com/4dqQnXI

go.nature.com

‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools

Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.

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Reposted by Tridib Mahata

Vivek Mutalik @vivekmutalik.bsky.social · 03/04/2026

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

Phage receptor prediction from genome sequencing alone. Bacterial receptor (blue) interacting with phage proteins (purple) is shown here

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Reposted by Tridib Mahata

Dor Salomon @drdorsalomon.bsky.social · 08/09/2025

🚨 Happy to share our new preprint in which we explore different layers of the phage-bacteria arms race. The highlight: phage homing endonucleases attenuate bacterial defenses 🤯 A 🧵... (1/7) #bacteriology #antiphage #T6SS www.biorxiv.org/content/10.1...

biorxiv.org

Phage-encoded homing endonucleases attenuate bacterial immunity

The arms race between bacteria and bacteriophages (phages) gave rise to multiple layers of antagonistic mechanisms, many of which remain unexplored. Here, we investigated the anti-phage defense system...

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