I am delighted to share that my work in the @aaronwhiteley.bsky.social lab is now on bioRxiv! We used a large-scale genetic screen to begin defining the vast landscape of phage proteins that trigger immune signaling in bacteria.
www.biorxiv.org/content/10.1...
biorxiv.org
Identifying phage proteins that activate the bacterial innate immune system
Bacteria have evolved sophisticated antiphage systems that halt phage replication upon detecting specific phage triggers. Identifying phage triggers is crucial to our understanding of immune signaling...