The manipulation of light by means of materials with varying refractive index distributions is widespread among natural systems and modern technologies. However, understanding how animals leverage ref...

Background We conducted an integrated cross-species spatial assessment of transcriptomic and metabolomic alterations associated with progression of intraductal papillary mucinous neoplasms (IPMNs), wh...

Acquiring subcellular-level three-dimensional (3D) tissue structures efficiently without damaging the tissue remains challenging in histopathology. Here, the authors integrate holotomography with deep...

Bats are important reservoirs of zoonotic pathogens, but suitable model systems for comprehensively exploring host-pathogen interactions and assessing spillover risks remain limited. To address this g...

Advances in label-free microscopy allow researchers to visualize the invisible in complex biological systems, even living animals, from whole organs down to the tiniest peptides.

Novel antimicrobial peptides (AMPs) are identified from the medicinal leech Hirudo nipponia using transcriptome analysis, AI-based in silico prediction, and optical diffraction tomography screening. ....

Researchers from VUMC are set to play a pivotal role at the American Association for Cancer Research Annual Meeting 2025.

Scientific Reports - Bafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron

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Intensive research efforts seek the discovery of efficient antimicrobial compounds to fight microbial resistance. Magnetic nanoparticles represent a p…

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