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Tom Grossmann

@tomngrossmann.bsky.social
428 followers 230 following 7 posts

Chemistry professor University of Göttingen (my views) #peptidomimetics | #proteomimetics | #incypro | co-founder #incircular | www.grossmannlab.com

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Tom Grossmann @tomngrossmann.bsky.social · 09/10/2026
We look for 2 PhD candidates to join our lab (EU project FlexCAT): 1) Structure-based design of peptide-derived β-catenin inhibitors (DC#9) 2) Semi-synthesis of modified β-catenin proteins (DC#10) Here is more information: phd-recruiting.medunigraz.at (deadline: October 31, 2026)
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Tom Grossmann @tomngrossmann.bsky.social · 29/05/2026
Excited to see our report on an #INCYPRO stabilised D-stereospecific hydrolase featured on the the inside cover of the current Angewandte issue! doi.org/10.1002/anie... Congrats to all coauthors and collaborators from the Bordusa Lab and Incircular. #ProteinEngineering #Biocatalysis
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Tom Grossmann @tomngrossmann.bsky.social · 29/03/2026
We report an #INCYPRO stabilised D-stereospecific hydrolase which operates efficiently at 50°C in 10% ethanol! The article in Angewandte Chemie originates from a collaboration with the Bordusa Lab and Incircular. Congrats to all authors! #ProteinEngineering #Biocatalysis doi.org/10.1002/anie...
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Tom Grossmann @tomngrossmann.bsky.social · 07/07/2025
After a decade @vuamsterdam.bsky.social I’m excited to share that I’m starting @uni-goettingen.de‬ I’m incredibly grateful for my supportive colleagues at the VU and looking now forward to the opportunities ahead. Big THANKS to everyone in the group who supported our research over the years!
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Tom Grossmann @tomngrossmann.bsky.social · 02/06/2025
Great to see our Highlight Review on TAV2b-derived RNA modulators online at Chemistry Letters doi.org/10.1093/chem... Congrats to first author Marvin Albers! Read more about our RNA-targeting strategies also here: -> doi.org/10.1002/anie... -> doi.org/10.1093/nar/... -> doi.org/10.1002/chem...
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Tom Grossmann @tomngrossmann.bsky.social · 28/04/2025
Great to see our paper on helicity-dependent peptide cyclizations online at the Journal of Peptide Science doi.org/10.1002/psc.... (open access) Congrats to all authors!! #peptidomimetics
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Tom Grossmann @tomngrossmann.bsky.social · 11/12/2024
Great to see so many familiar & new faces here! Read on our biomimetic design strategies: www.thieme-connect.com/products/ejo... 👉 #proteomimetics for challenging targets 👉 #INCYPRO chemical #proteinengineering 👉 covalent #peptidomimetics inhibitors Big thanks to all former & present group members!
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