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Tiphaine Le Roy 🦠

@titicaccae.bsky.social
1.4K followers 1.4K following 94 posts

Research Scientist at Sorbonne Université / INSERM 🇫🇷 • Gut Microbiome • Small Intestine • Obesity & Metabolic diseases • new PI 😱 • 🐁🦠🧫💩

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Reposted by Tiphaine Le Roy 🦠
Alan Walker @faecalmatters.bsky.social · 17/09/2026
Formal announcement of the 15th installment of the International Gut Microbiology Symposium series, running from June 1st to 3rd 2027: www.abdn.ac.uk/events/confe... We will look forward to welcoming old friends and new to Aberdeen next summer.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 31/03/2026
Hoho… @contamclub.bsky.social #MicroSky #microbiomesky
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 30/03/2026
A good start to the week 🫠🦠🧫 #Microbiome #MicroSky
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 20/02/2026
We love Reviewer 2, but he frightens us 🫣. ... are you our Reviewer 2 this time 👀?
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 20/02/2026
You know you are in trouble when Reviewer 2 starts by saying that they have '𝙚𝙭𝙖𝙢𝙞𝙣𝙚𝙙 𝙩𝙝𝙚 𝙡𝙞𝙩𝙚𝙧𝙖𝙩𝙪𝙧𝙚 𝙤𝙣 𝙩𝙝𝙞𝙨 𝙩𝙤𝙥𝙞𝙘 𝙞𝙣 𝙙𝙚𝙩𝙖𝙞𝙡 𝙖𝙣𝙙 𝙧𝙚𝙫𝙞𝙚𝙬𝙚𝙙 𝙝𝙤𝙬 𝙩𝙝𝙞𝙨 𝙚𝙨𝙩𝙞𝙢𝙖𝙩𝙚 𝙞𝙨 𝙙𝙚𝙧𝙞𝙫𝙚𝙙'. 🧫 🦠🧪 #ESR #microbiome #MicroSky #microbiome #science #PhDSky #AcademicSky
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 19/01/2026
ho 😢 www.embl.org/news/embl-an...
embl.org
In remembrance of Peer Bork  | EMBL
EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 26/11/2025
the kind of work I absolutely love !
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Reposted by Tiphaine Le Roy 🦠
Kate Coldwell @katecoldwell.bsky.social · 12/08/2025
Location in the digestive tract matters! 💩 microbiota ≠ duodenal microbiota As our understanding of the effect of the #microbiome in #PSC grows, it beomes more nuanced. #LetsBeatPSC #primarysclerosingcholangitis
researchgate.net
Reconsidering the microbial origins of primary sclerosing cholangitis and related autoimmune disorders: A case for the antro‐duodenal microbiome | Request PDF
Request PDF | On Aug 5, 2025, Richard Kellermayer and others published Reconsidering the microbial origins of primary sclerosing cholangitis and related autoimmune disorders: A case for the antro‐duod...
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 16/07/2025
Some people can't even do a proper copy-paste 🤷‍♀️
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 05/07/2025
😂😂 not sure it will enhance it significantly but go ahead 😂
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 05/07/2025
Agora2 ? I’m not a specialist in the field but I am very interested by this subject and what you will find 😅
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 30/04/2025
We are currently discussing in the lab putting all our codes on github before publication, as you can understand, it makes me nervous that the code could be retrieved by someone even in private mode before the studies are published 😅 and I would like to send the original post to my colleagues.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 30/04/2025
1/2. a few month ago, I saw someone her and/or on Linkedin telling that he discovered that his private code on github was stolen and used in a paper not acknowledging him. I can't find it, does someone remember this and send me the link to the original post ? #science
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/03/2025
This a nice piece of work from a mechanistic point of view, but considering the detrimental effect of Peptostreptococcus anaerobius on colorectal carcinogenesis and resistance to immuno-therapies, do we know if other bacteria have a similar hability to ferment proline ?
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 03/03/2025
Standardized mouse model GM15 www.nature.com/articles/s41...
nature.com
A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes - Nature Communications
Here, the authors develop and characterize a mouse microbiota composed of 15 strains representative of the intestinal microbiota found in C57BL/6J specific opportunistic- and pathogen-free (C57Bl/6J S...
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Reposted by Tiphaine Le Roy 🦠
Hilda Bastian @hildabast.bsky.social · 14/02/2025
Hate that it has come to this, but it's time to consider PubMed vulnerable to enshittification. My latest post @plos.org discusses the lines we need to fight to hold – and alternatives we can rely on internationally: absolutelymaybe.plos.org/2025/02/14/w... #medlibs
absolutelymaybe.plos.org
What if We Can't Rely on PubMed? - Absolutely Maybe
PubMed is incredibly reliable. And a lot depends on it. It’s an ecosystem built around MEDLINE, the steady feed of new publications…
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Reposted by Tiphaine Le Roy 🦠
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 10/02/2025
technically not a problem if you eat the whole cake by yourself 🦠 🎂 🤔
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Reposted by Tiphaine Le Roy 🦠
Trends in Microbiology @cp-trendsmicrobiol.bsky.social · 06/02/2025
📢Sarah Lebeer (@sarahlebeer.bsky.social) and colleagues at the Isala team call for a more comprehensive, global, and inclusive understanding of the #vaginal #microbiome, critically reflecting on the use of 'race' and 'ethnicity' in studies. Read the Opinion piece here: www.cell.com/trends/micro...
cell.com
Diversity in women and their vaginal microbiota
Women’s health is essential to global societal and economic wellbeing, yet health disparities remain prevalent. The vaginal microbiota plays a critical role in health, with research indicating that re...
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 28/01/2025
And…. I didn’t get it 🙃😭. At least it was fast. (𝘛𝘳𝘺𝘪𝘯𝘨 𝘵𝘰 𝘯𝘰𝘳𝘮𝘢𝘭𝘪𝘻𝘦 𝘳𝘦𝘫𝘦𝘤𝘵𝘪𝘰𝘯 𝘩𝘦𝘳𝘦 𝘣𝘦𝘤𝘢𝘶𝘴𝘦 𝘪𝘵 𝘪𝘴 𝘩𝘢𝘳𝘥 𝘵𝘰 𝘩𝘢𝘯𝘥𝘭𝘦.) bsky.app/profile/titi...
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Reposted by Tiphaine Le Roy 🦠
Nature Reviews Microbiology @natrevmicro.nature.com · 24/01/2025
#weekendreading🔬 Cardiometabolic benefits of a non-industrialized-type diet are linked to gut microbiome modulation @cellpress.bsky.social #microsky #microbiome #diet www.cell.com/cell/fulltex...
cell.com
Cardiometabolic benefits of a non-industrialized-type diet are linked to gut microbiome modulation
Is it possible to restore the human gut microbiome in industrialized settings and reintroduce microbial species that have been lost? In healthy adults, Li et al. found that consuming a diet mimicking ...
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 24/01/2025
bsky.app/profile/titi...
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 24/01/2025
... colossal amounts of wet lab work and, at least in my experience, it is not easy to get funding for such projects.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 24/01/2025
www.nature.com/articles/s41... Hold my beer (ℎ𝑒𝑎𝑑𝑠 𝑜𝑓𝑓 𝑡𝑜 𝑡ℎ𝑒 𝑚𝑖𝑐𝑟𝑜𝑏𝑖𝑜𝑙𝑜𝑔𝑦 𝑙𝑎𝑏). 🧫 🦠🧪 Kidding aside, I completely agree that classical microbiological approaches are crucial to address causality and mechanisms. However, it requires... #MicroSky #microbiomesky #science
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Epsiloon @epsiloon.com · 17/01/2025
Au fait, on s'est dit qu'il fallait quand même qu'on vous propose aussi un kit avec les adresses de toute l'équipe d'Epsiloon. Parce que oui, on est tous là maintenant. Bienvenue ! go.bsky.app/3EFfgk2
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 04/01/2025
Nope, our holidays are not their priority. Last summer a 5th sept deadline from the ANR screwed up my summer holidays 😭. Hope you got the grant (I didn’t 🫠)
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 04/01/2025
Ho I could 100% have missed it 😬😇.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 03/01/2025
I hope so… but if they decide to give me money they can take as long as they want 😂
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 03/01/2025
French diabetes association 😅
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 03/01/2025
Me realising that the deadline for a grant submission is sunday night, not monday night, and that I need to cut my holiday short now, not tomorrow. 🧫 🦠🧪#esr #MicroSky #microbiomesky #PhDSky #AcademicSky
media.tenor.com
a man in a suit and tie is standing in the rain and crying .
ALT: a man in a suit and tie is standing in the rain and crying .
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Reposted by Tiphaine Le Roy 🦠
Carl T. Bergstrom @carlbergstrom.com · 16/12/2024
Many of my students and a few of my colleagues run their writing through an LLM to improve the prose. LLMs can make bad writing better, but they can just as easily make decent writing worse. Note the lack of flow and the added redundancy in the example below.
ChatGPT 4.o

QUERY: Improve this:

"Ask an LLM to rephrase an awkward sentence.

You can judge for yourself whether its suggestion improves your original text."


RESPONSE: "Ask a language model to rephrase an awkward sentence and see if the result enhances your original wording. You can decide for yourself if its suggestion is an improvement."
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Reposted by Tiphaine Le Roy 🦠
Maxime Delorme @mdelorme.bsky.social · 15/12/2024
J'en ai PLEIN LE FIAK de voir les gens foutre de l'IA partout même s'il y en a pas besoin, puis de casser les miches aux gens un peu réfractaires en mode "Ohlala c'est juste un outil ce qui est important c'est comment on s'en sert".
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 12/12/2024
Many microbiologists probably already know this, but I was today years old when I learned that 𝘛𝘶𝘳𝘪𝘤𝘪𝘣𝘢𝘤𝘵𝘦𝘳 𝘴𝘢𝘯𝘨𝘶𝘪𝘯𝘪𝘴 is filamentous 😅. #MicroSky #microbiomesky 🧫 🦠🧪
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/12/2024
I have to tag @arthremys.bsky.social and her profile picture featuring the « new » lab when our institution made us leave our old lab 😂😂
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/12/2024
I know 100% that this doesn't mean my project proposal was crap, but every rejection hurts. 🦠🧫#esr #microbiome #MicroSky #microbiomesky #science
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/12/2024
I also study host-microbe interaction in the context of metabolic diseases, could you add me please.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 02/12/2024
I am guilty of using the term "gut microbiome" many times in studies based on the fecal microbiota analyses, but yes, you are right and we should be more carreful to use the right term.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 02/12/2024
It's certainly more complicated and invasive, but it can be done, we and other have done it recently, using endoscopy or ingestible capsules. Each technique has its limitations though...
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 28/11/2024
Let's grow some bugs 😎🦠🧫 @leibniz-dsmz.bsky.social #microbiome #MicroSky #microbiomesky
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Reposted by Tiphaine Le Roy 🦠
PubPeer @pubpeer.com · 25/11/2024
And now for the announcement: While many of our plans for the award funds will take time to implement, one can start immediately. To thank our users and encourage scientific debate, we’re introducing $1,000 rewards for selected PubPeer comments! Yes students and postdocs you read that right: $1000
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 23/11/2024
I took it every day for 4 years and never realized 😂🦠
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 16/11/2024
Bienvenue Dr Caca ! Dr es fèces
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 09/11/2024
Not that I am aware of, but an alternative is to go on the #MicroSky feed and follow all the people who liked the feed.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 09/11/2024
Hi ! I’m a scientist work on the gut microbiota and its role in metabolic diseases (with a recent focus on the small intestinal microbiota), may I be added to the list ?
media.tenor.com
a close up of a cat with big eyes
ALT: a close up of a cat with big eyes
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 06/11/2024
borrowed to @GrumpyReviewer2, this is so accurate right now. #esr #PhDSky #AcademicSky
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David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 14/10/2024
What? What do you wear to the biggest professional event in your field? #IMCC7
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/10/2024
3/3 Strikingly, the composition of the duodenojejunal microbiota appeared to be more closely related to the clinical status of the participants than that of the oral or faecal microbiota, suggesting that the microbiota of this segment of the gut plays a critical role in regulating host metabolism.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/10/2024
2/3 We studied the composition of the microbiota in the saliva, duodenojejunal fluid and faeces of 15 normal weight and 15 obese participants. We observed a reduction in the abundance of the familly Neisseriaceae and an increase in diversity in the obese participants.
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 07/10/2024
1/3. My first article as a (co) last author is out today in Gut Microbes 🎉: Comparative analysis of the duodenojejunal microbiome with the oral and fecal microbiomes reveals its stronger association with obesity and nutrition. #MicroSky #microbiomesky 🧪🦠 url6649.tandfonline.com/ls/click?upn...
url6649.tandfonline.com
Comparative analysis of the duodenojejunal microbiome with the oral and fecal microbiomes reveals its stronger association with obesity and nutrition
The intestinal microbiota is increasingly recognized as a crucial player in the development and maintenance of various chronic conditions, including obesity and associated metabolic diseases. While...
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Tiphaine Le Roy 🦠 @titicaccae.bsky.social · 02/10/2024
I exchanged 8 emails with a supplier during the last two days to explain him how to get paid by our institution. I'm loosing it, I want to go back to the lab and actually do #science. et vive l' #ESR. #PhDSky #AcademicSky
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DSMZ Digital Diversity @dsmzd3.bsky.social · 12/07/2024
#SILVA release 138.2 has been published 🧬🖥️. For more information see arb-silva.de/news/view/20... #SILVAngs will be updated next week. #DSMZDigitalDiversity #biology #databases 🦠🌱🧪
arb-silva.de
News Item
SILVA provides comprehensive, quality checked and regularly updated databases of aligned small (16S / 18S, SSU) and large subunit (23S / 28S, LSU) ribosomal RNA (rRNA) sequences for all three domains ...
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