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Tiago G. Zeferino

@tiagogzeferino.bsky.social
461 followers 1.3K following 8 posts

PhD student in Jacob Koella's lab at Neuchâtel | Evolutionary biologist interested in how host-parasite interactions evolve and influence each other | he/him | 📍Neuchâtel, Switzerland

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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 26/04/2025
@tiagogzeferino.bsky.social and I just showed Dexrazoxane is a #microsporidian growth-control drug in #Anopheles in our latest paper. Out now in Acta Tropica, below 👇 #MicroSky www.sciencedirect.com/science/arti...
sciencedirect.com
Dexrazoxane as a viable microsporidia control agent in Anopheles gambiae
Microsporidia have long been proposed as biological agents for controlling disease vectors and the parasites they transmit. However, their study in ve…
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Reposted by Tiago G. Zeferino
Trends in Parasitology @cp-trendsparasitol.bsky.social · 28/03/2025
New Parasite of the Month: #Vavraia #culicis, a #microsporidian infecting several genera of #mosquitoes, authored by @luismsilva.bsky.social @tiagogzeferino.bsky.social & J. Koella. #Aedes #Culex #Anopheles #Culiseta #Ochlerotatus #Orthopodomyia @science.ubc.ca authors.elsevier.com/a/1kpZQ5Eb1x...
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 24/03/2025
Check out our latest overview of Vavraia culicis, now at @cp-trendsparasitol.bsky.social! A really cool widespread microsporidian parasite! @tiagogzeferino.bsky.social authors.elsevier.com/a/1kpZQ5Eb1x...
authors.elsevier.com
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 29/01/2024
First pre-print of the year 🥳 Curious about how infection complexity and transmission affect the classical ideas of virulence evolution? Check our new paper! Also, this thread 1/7
doi.org
Complex interactions in the life cycle of a simple parasite shape the evolution of virulence
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 25/05/2024
Pt2 of our transmission selection lines saga is out now! Here we applied our new transmission framework to demonstrate how virulence evolution can only be understood by integrating parasite evolution within and outside the host. See below and share :) www.biorxiv.org/content/10.1...
biorxiv.org
Virulence evolution: thinking outside of the host
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 25/07/2024
And I also advice you to check Tiago’s work, also from Koella’s lab for some nice insights into parasite evolution, its adaptation potential and how it might affect vector control :) in the same room, just a bit before!
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 23/09/2024
My latest (and first solo) preprint is now out! 🥳 biorxiv.org/content/10.1... If you are into #Anopheles immune response, parasite #transmission or #microsporidia, this one is for you :) Check the thread below.
biorxiv.org
Selection on time to parasite transmission shapes the host Anopheles gambiae transcriptional response and suggests immune evasion
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 30/11/2024
Did you know that the presence of #Pseudomonas spp. in the water bodies where #Anopheles mosquitoes grow can increase their resistance to #insecticide? 🦟 🦠 Curious? Check our paper below! :) rdcu.be/d1UmA #MicroSky #SymbioSky #EvoSky
rdcu.be
Exposure to Pseudomonas spp. increases Anopheles gambiae insecticide resistance in a host-dependent manner
Scientific Reports - Exposure to Pseudomonas spp. increases Anopheles gambiae insecticide resistance in a host-dependent manner
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 18/12/2024
Also interested in disease behaviour? Check Tiago’s (Super cool!) new preprint on how mosquitoes choose the best diet for the infection phase they are in - based on the antioxidant/prooxidant content of the diet! #Anopheles #MicroSky #BlueSky #EvoSky
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 18/12/2024
The last part of our transmission lines saga is out now! 🦟 🦠 Here we show several #Anopheles host effectors that are parasite-specific and/or virulence-dependent to a #microsporidia via metallomics, diet manip and resource dynamics. www.biorxiv.org/content/10.1... #EvoSky #SymbioSky #MicroSky
biorxiv.org
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 23/12/2024
Check Tiago’s part2 preprint for the physiology of self-medication in #Anopheles #EvoSky #SymbioSky #MicroSky
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 16/12/2024
Ever wondered how life history impacts an organism energy reserves? Well check our latest preprint below www.biorxiv.org/content/10.1... Turns out, the presence of certain energetic shifts is a stronger predictor of survival! #EvoSky #MicroSky
biorxiv.org
Energetic shifts predict the mortality of Anopheles gambiae
Life history theory predicts that resource allocation adapts to ecological and evolutionary pressures. We investigated resource and energy dynamics in the malaria vector Anopheles gambiae after exposu...
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Reposted by Tiago G. Zeferino
Luís M. Silva @luismsilva.bsky.social · 17/10/2024
In need of a drug that suppresses microsporidian growth within a mosquito? Check our latest mini-preprint below :) (A thread 1/4) doi.org/10.1101/2024...
doi.org
Dexrazoxane as a viable microsporidia control agent in Anopheles gambiae
Microsporidia have long been proposed as biological agents for controlling disease vectors and the parasites they transmit. However, their study in vector biology has been constrained due to challenge...
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