Super-large targeted Knock-Ins in primary T cells, with multigene inserts >8kb, in a single reaction. HOW?? 🙀
Combine simple CRISPR-HDR & Integrases for one-pot PASTA🍝
= Programmable And Site-specific Transgene Addition. 😎
Jonas Kath
@therealjonaskath.bsky.social
52 followers 93 following 2 posts
Physician Scientist | Genome Engineering | CAR T cells