Our new preprint is available and on a journal editor’s desk somewhere…Drug-resistant osteosarcoma tumour spheroids, combined chemotherapy treatments with a hypoxia-activated pro-drug and applied integrated spatial multimodal mass spectrometry imaging or tumour responses. doi.org/10.64898/202...
doi.org
Hypoxia-activated prodrug and chemotherapy disrupt resistance-associated metabolism in osteosarcoma
Chemotherapy resistance remains a critical barrier in treating osteosarcoma. Hypoxia-activated prodrugs (HAPs) target oxygen-deprived tumor regions that evade conventional chemotherapy. Here, we appli...
