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Toronto Cannabis and Cannabinoid Research Consortium

@tc3consortium.bsky.social
218 followers 180 following 133 posts

TC3 is an interdisciplinary research network that brings together and supports researchers and trainees engaged in cannabis & cannabinoid research at the University of Toronto & Toronto Academic Health Sciences Network.

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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/09/2026
#clinicalpharmacology #clinical #pain #mentalhealth #substanceusedisorders #parkinsons #parkinsonsdisease #research
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/09/2026
Lola is seeking postdoctoral opportunities in clinical cannabinoid research, with interests in pain, mental health, substance use disorders. @uoftmedicine.bsky.social #PhDLife #EarlyCareerResearcher #PostdocPosition #cannabinoid #endocannabinoid #cannabinoid #endocannabinoid #clinicalresearch
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/09/2026
Meet @tc3consortium.bsky.social Fellow Lola Zovko! Lola is a PhD candidate in the Department of Pharmacology and Toxicology at the @utoronto.ca, supervised by Dr. Ali Salahpour. Her doctoral work focuses on the effects of endocannabinoid modulation in an acute mouse model of Parkinson's disease.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 03/09/2026
Through randomized controlled studies, these projects examine how THC potency and dose influence acute impairment, with the goal of informing road safety and public health guidance. #cannabis #roadsafety #driving #publichealth #edibles #PhDLife #AcademicCommunity #Research
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 03/09/2026
His doctoral research focuses on the effects of varying doses of smoked and edible cannabis on simulated driving performance, cognition, and subjective mood experiences.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 03/09/2026
Meet @tc3consortium.bsky.social Fellow Adam Zaweel, Pharm.D.! Adam is a PhD candidate in the Department of Pharmacology and Toxicology at the @utoronto.ca, co-supervised by Dr. Bernard Le Foll and Dr. Christine Wickens at the Centre for Addiction and Mental Health (@camhnews.bsky.social ).
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 31/08/2026
... for the treatment of substance use disorders, including alcohol use disorder, tobacco use disorder, and cannabis use disorder. 3/3
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 31/08/2026
She works with Professor Christian Hendershot in the USC Department of Population and Public Health Sciences conducting clinical trials and human laboratory studies focused on incretin-based therapies (e.g., GLP-1 receptor agonists and GLP-1/GIP receptor agonists)... 2/3
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 31/08/2026
Congratulations to @tc3consortium.bsky.social Fellow Alumna Maryam Sorkhou on completing her doctoral studies at the @utoronto.ca! Maryam began working as a Postdoctoral Research Associate at the @usc.edu in August 2026. 1/3 #PhDLife #AcademicCommunity #Congratulations
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 27/08/2026
Their findings suggest that Ontario's legal cannabis market is trending toward lower-cost, higher-potency products, a pattern that may have implications for consumer purchasing behavior and public health outcomes. #cannabis #ontario #onpoli #THC #drugpolicy #publichealth
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 27/08/2026
👉 THC potency of cannabis products has 📈 since 2022 👉Prices for most flower products, disposable vapes, thread cartridges, and soft chews have significantly 📉 👉Edible products, particularly gummies, and disposable vapes 📈 in market share 👉The total number of products available on the legal market 📉
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 27/08/2026
The team analyzed 1,727 products listed on the Ontario Cannabis Store, the province's sole legal wholesaler, and compared findings to their previous 2022 dataset. Here is what they found:
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 27/08/2026
on a study to investigate trends in cannabis products, potency, and pricing in Ontario's legal recreational market, five years after federal legalization.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 27/08/2026
What does Ontario's legal cannabis market look like a few yrs post-legalization? @tc3consortium.bsky.social Trainee, Paulina Antwi, Fellow Alum, Justin Matheson & Members, Profs Christine Wickens, Bernard Le Foll, Sergio Rueda & Patricia Di Ciano, collaborated... pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
An update on cannabis products, cannabinoid content, plant type, and prices five years after legalization in Ontario, Canada
Changing trends in legal recreational cannabis markets necessitates the continuous monitoring of important market metrics such as price, potency, type, and availability of cannabis products which may ...
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 10/08/2026
This systematic review examined the impact of repetitive transcranial magnetic stimulation (rTMS) on sleep in individuals with substance use disorders.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 10/08/2026
Congratulations to TC3 trainees Anna Mouzenian, Christina Pereira & Dhvani Mehta and Members Drs. Victor Tang, Matthew E Sloan & Stefan kloiber on their recent publication pubmed.ncbi.nlm.nih.gov/42372632/ #sleep #treatment #SUD @camhnews.bsky.social
pubmed.ncbi.nlm.nih.gov
The effects of repetitive transcranial magnetic stimulation on sleep in individuals with substance use disorders: A systematic review - PubMed
Understanding the effects of rTMS on sleep in SUDs is crucial for improving treatment strategies. Findings suggest that rTMS may improve sleep in this population, but further studies using objective s...
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 04/08/2026
Dr. Matheson hopes to soon start their own lab to explore how biological and sociocultural factors converge to impact substance use health and to build towards development of sex- and gender-informed treatments for SUDs. #cannabis #THC #cannabinoid #research #driving #sex #gender #SUD #Treatment
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 04/08/2026
Their own research program focuses on understanding how sex, gender, and intersecting social factors influence cannabis use and substance use health, with the goal of improving prevention and treatment of substance use disorders (SUDs). @camhnews.bsky.social
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 04/08/2026
Meet @tc3consortium.bsky.social Fellow Alum Dr. Justin Matheson @justinrmatheson.com! Dr. Justin Matheson is currently the Research Manager of the Driving Simulator Laboratory at the Centre for Addiction and Mental Health, where they support a range of projects related to cannabis and impairment.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 23/07/2026
Thank you to everyone who brought their lived expertise, research, collaborative spirit and curiosity. tinyurl.com/ckxjptvz #EDI #Workshop #EDIA #Accessiblity #ScientificInnovation #Collaboration #Throwback #AcademicLife #Equity #Diversity #Inclusion
tinyurl.com
Recap - 2026 TC3 EDI Workshop
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 23/07/2026
The lessons learned, interesting data, and insightful discussions and perspectives from that intensive day are still with us. A huge thank you to our lead organizers, Justin Matheson, Catharine Mielnik, & Christina Pereira, and engaged participants. @justinrmatheson.com @camielnik.bsky.social
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 23/07/2026
Reflecting back on the incredible energy from our 2nd Annual Workshop on Equity Diversity Inclusion and Accessibility in #cannabis and #cannabinoid #research at the @utoronto.ca earlier this summer.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/07/2026
#Alzheimer #MAGL #endocannabinoid #cannabinoidreceptor #CB1 #sexdifferences #diagnosis #treatment #AD #betaamyloid #PETimaging
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/07/2026
These results indicate that the endocannabinoid system may be a promising target not only for the treatment of AD, but also for its diagnosis. This work adds to the growing body of evidence underscoring the need to consider sex differences in diagnostics and drug development.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/07/2026
Their findings show that both the CB1 #cannabinoid receptor and the endocannabinoid-degrading enzyme, MAG lipase are altered in an age-, sex- and pathology-specific manner, beginning in the early stages of beta amyloid pathology.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 22/07/2026
Are there any changes in the #endocannabinoid system in #Alzheimer’s Disease (AD)? This is the question @tc3consortium.bsky.social Trainee Alumna, Anna Pees, Member, Neil Vasdev, & team set out to answer using PET imaging in a mouse model of AD. @uoftmedicine.bsky.social www.thno.org/v15p3368.htm
thno.org
Sex- and age-specific sensitivities of the endocannabinoid system in Alzheimer's disease revealed by PET imaging with [18F]FMPEP-d2 and [18F]MAGL-2102
Sex- and age-specific sensitivities of the endocannabinoid system in Alzheimer's disease revealed by PET imaging with [<sup>18</sup>F]FMPEP-<i>d</i><sub>2</sub> and [<sup>18</sup>F]MAGL-2102
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 20/07/2026
and larger randomized trials to replicate these findings and clarify the mechanisms linking abstinence to symptom changes in patients with comorbid PTSD and CUD. #cannabis #PTSD #recovery #CUD #psychiatry #clinicaltrial #patienteducation
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 20/07/2026
Recommendations stemming from this study include routine assessment of cannabis use throughout PTSD treatment, patient education on the potential consequences of continued use ++
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 20/07/2026
The team found that sustained cannabis abstinence over 12 weeks was associated with reduced PTSD symptom severity and frequency. These findings challenge the assumption that long-term cannabis use improves symptoms or functioning in individuals with PTSD. Instead, it could limit recovery.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 20/07/2026
@tc3consortium.bsky.social fellows, Justyne Rodas (alum) & Maryam Sorkhou, & Members, Drs. Tony George, Stefan Kloiber & Ahmed Hassan, collaborated on a preliminary open-label study to assess impact of cannabis abstinence on symptoms of PTSD in people with comorbid PTSD & CUD. tinyurl.com/yc2d4ebd
tinyurl.com
The Effects of Extended Cannabis Abstinence in Comorbid Posttraumatic Stress Disorder and Cannabis Use Disorder
Participants who achieved abstinence reported significantly greater reductions in total PTSD symptom severity and symptom count compared to those who did not.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 16/07/2026
No significant effects were observed on other neuropsychiatric symptoms although additional research is required.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 16/07/2026
Overall, #cannabinoids may help reduce #agitation in people living with severe #dementia and efficacy was significant at doses of at least 10 mg THC. Cannabinoids were well-tolerated overall, albeit with sedative effects more commonly reported in the cannabinoid group.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 16/07/2026
@tc3consortium.bsky.social Fellow Hui Jue Wang and Members, Drs. Krista Lanctot and Walter Swardfager collaborated on a systematic review and meta-analysis to assess the efficacy and safety of #cannabinoids for #neuropsychiatric symptoms of #Dementia. link.springer.com/article/10.1...
link.springer.com
Efficacy and Safety of Cannabinoids for Neuropsychiatric Symptoms of Dementia: A Systematic Review with Meta-analysis - CNS Drugs
Background and Objective Neuropsychiatric symptoms (NPS) are highly prevalent in persons with dementia and have been associated with adverse health outcomes. Neuropsychiatric symptoms can impose major...
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 16/07/2026
No significant effects were observed on neuropsychiatric symptoms although additional research is required.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 16/07/2026
Overall, #cannabinoids may help reduce #agitation in people living with severe #dementia and efficacy was significant at doses of at least 10 mg THC. Cannabinoids were well-tolerated overall, albeit with sedative effects more commonly reported in the cannabinoid group.
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Reposted by Toronto Cannabis and Cannabinoid Research Consortium
Justin Matheson, PhD (he/they) @justinrmatheson.com · 26/06/2026
Heading off to France for #ICRS2026 Re-sharing the cannabis starter pack I made since I haven't updated this in a long time - let me know if you want to be added!
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 14/07/2026
The findings reinforce the importance of public health education and research especially as high potency cannabis is increasingly available. #cannabis #driving #roadsafety #impaireddriving #THC #smoking #publichealth
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 14/07/2026
The study investigated the impact of Δ9-THC potency in smoked cannabis on driving performance and showed that higher potency cannabis was associated with greater driving impairment, uncovering potency-dependent impairments in simulated driving exercises.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 14/07/2026
Check out the recent collaborative paper by @tc3consortium.bsky.social fellows and trainees Adam Zaweel, @justinrmatheson.com, Madison Wright, PhD and TC3 members Bernard Le Foll, Bruna Brands, Beth Sproule, Christine Wickens, and Patricia Di Ciano et al. www.nature.com/articles/s41...
nature.com
Potency-related effects of smoked cannabis on simulated driving performance: a randomized, controlled crossover trial - Scientific Reports
Scientific Reports - Potency-related effects of smoked cannabis on simulated driving performance: a randomized, controlled crossover trial
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 13/07/2026
We wish Mikayla success in her long term goal of pursuing a MA/PhD in Clinical Psychology!
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 13/07/2026
She is also a clinical research assistant in the Cognitive Brain Health Lab at Sunnybrook Health Sciences Centre where she is supporting studies related to menopause and women’s brain health.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 13/07/2026
She is currently a research assistant in the Trauma Informed Responses Research Group at OISE where she supports several projects focusing on the experiences of survivors of intimate partner violence.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 13/07/2026
Congratulations to @tc3consortium.bsky.social Trainee Alumna Mikayla Lisi 🙌🎉 Mikayla recently graduated with a Master of Education in Developmental Psychology from the Ontario Institute for Studies in Education at UofT @utoronto.ca #AcademicCommunity #AcademicLife #PhDLife #Research
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 13/07/2026
She is currently a research assistant in the Trauma Informed Responses Research Group at OISE where she supports several projects focusing on the experiences of survivors of intimate partner violence.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 03/07/2026
She hopes that her research will enhance our understanding of the endocannabinoid system in SAD and support the research of future endocannabinoid-targeting treatments.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 03/07/2026
Christina's research focuses on using neuroimaging to investigate the endocannabinoid enzyme, fatty acid amid hydrolase, in individuals with social anxiety disorder (SAD) and how it may be involved in social stress response.
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 03/07/2026
Meet @tc3consortium.bsky.social Fellow Christina Pereira! Christina is a PhD. candidate at the Institute of Medical Science, Temerty Faculty of Medicine, University of Toronto under the supervision of Dr. Isabelle Boileau and Dr. Stefan Kloiber. #endocannabinoid #socialanxiety #stress
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 29/05/2026
Dr. Victor Tang, Dr. James MacKillop, Dr. Iris Balodis and Dr. Karim Ladha. #cannabis #canada #research
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 29/05/2026
TC3 is kicking off day 3 of the 2026 Canadian Cannabis Research Summit co-hosted with @ccicbluesky.bsky.social @utoronto.ca with a electric panel on the "Opportunities and Challenges for Cannabis Researchers in Canada" Panelists included CIHR-INHMA Scientific Director, Prof. Patricia Conrod,
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Toronto Cannabis and Cannabinoid Research Consortium @tc3consortium.bsky.social · 29/05/2026
We are excited to have you at this year's Canadian Cannabis Research Summit, Dr. Hurd @neurovoice.bsky.social ! Looking forward to your talk this afternoon. @ccicbluesky.bsky.social
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