Sign in

Thomas Swift

@swifthom.bsky.social
167 followers 121 following 74 posts

Lecturer at a Northern University, ex-Programme lead for Apprentices, Polymer Chemist and fiction aficionado.

PostsRepliesMedia
Thomas Swift @swifthom.bsky.social · 18/06/2026
Nice to step away from spinout updates and highlight an academic collaboration paying off. Hard working colleague's Refaat Hamed’s work just published in ACS Catalysis: pushing enzyme engineering into some very challenging chemical space. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Breaking the N-Alkyl Barrier: Enzyme−Substrate Co-Engineering of Fe(II)/2-Oxoglutarate-Dependent Hydroxylases for N-Heterocyclic Amino Acids
Hydroxylation and N-alkylation are powerful, orthogonal handles for modulating the conformation and drug-like properties of amino acid-derived scaffolds, yet doubly substituted, stereodefined N-alkyl ...
010
Thomas Swift @swifthom.bsky.social · 30/06/2025
A peer reviewed paper just got accepted - and I'm torn between sharing good news with my collaborators and sampling local Hyderabadi Indian cuisine. #toughchoices
030
Reposted by Thomas Swift
Molecular Titans Ltd @moleculartitans.bsky.social · 27/06/2025
The family is growing! We are delighted to be hosting a summer intern to validate our process Chemistry. In turn Kiera is becoming our 'first' temporary employee of Moleculsr Titans!
011
Thomas Swift @swifthom.bsky.social · 11/06/2025
So... today I was at an infectious disease conference and I finally saw in black and white an answer COVID grifters spent 2020/21 meaning about. 'Where is the evidence N95 masks help prevent COVID?' Well. It exists. Now. Finally. It takes time to do high quality science and full data integrity...
120
Thomas Swift @swifthom.bsky.social · 10/06/2025
So today, I presented in Rome at a Global Infectious Disease congress, my PhD student is presenting in Sheffield @YRM_2025 and all appears to have been a grand success. No idea how she's celebrating but my hotel has a pool..
Infectious disease congressMy talk seemed to go down wellEvening plans by pool are sorted
000
Thomas Swift @swifthom.bsky.social · 08/06/2025
Work has sent me to Rome, but I got 1 afternoon free today to get bus into centre to explore. Crazy to think a generation of people 'sort of' know this city intimately because of Assassin's Creed games - and I'm glad to say it didn't disappoint exploring!
I've spent many hours exploring s virtual Castel Saint'angelo - now I've seen the real thing finally!
010
Thomas Swift @swifthom.bsky.social · 21/05/2025
My PhD student delivered a faculty 3 minute thesis competition yesterday and I've had good feedback - unfortunately work meant I was 50 miles north at the time so had to miss out. A great dry run before she presents at the Macro YRM in Sheffield on the 10th of June! #polymerchemistry
PhD candidates getting certificates after 3 minute thesis
000
Thomas Swift @swifthom.bsky.social · 04/05/2025
Lot of people voted reform because they are unhappy main political parties. But I'm yet to see any evidence Nigel Farage and his ilk are not grifters. Take the country seriously and stop mucking up every day British peoples livelihoods you schmooks www.independent.co.uk/news/uk/poli...
independent.co.uk
Reform mayor vows to sack council’s diversity officers - except there aren’t any
Dame Andrea Jenkyns has doubled down on Farage’s pledge to sack diversity officers in Lincolnshire but the county council has revealed it does not employ any
000
Thomas Swift @swifthom.bsky.social · 01/05/2025
My smart watch has started telling me things I already knew! Still... Nice to have it documented. Self improvement is hard
Health app screenshkt reports that April was a very stressful month
010
Thomas Swift @swifthom.bsky.social · 30/04/2025
Leeds City Centre is showing its best face for the BSRC Sparking Innovation conference! Park Plaza conference suite has open glass walls facing out over the city hall. Joined them to find out and contribute to the future of innovation funding opportunities available and upcoming in this sector
000
Thomas Swift @swifthom.bsky.social · 10/04/2025
First night of the Rothwell Beer Festival, kicking off 3 days of responsible drinking to raise money to charity! Always a stressful moment as we kick off the event, getting purchases sorted and ticket sales going, but I feel like everything will be alright!
Warm weather in the parish grounds for festival goers4o cask Ales available behind the bar
110
Thomas Swift @swifthom.bsky.social · 08/04/2025
Some things to celebrate after today. A fantastic day networking followed by a stroke of well timed news. Looking forward to the opportunities this will bring over the summer!
Port and cheese
020
Thomas Swift @swifthom.bsky.social · 08/04/2025
Delighted to have just given @moleculartitans.bsky.social their first public outings, discussing needs within public health authorities and how our materials offer new routes forward, at the @bionow.bsky.social Yorkshire Partnering event. Hopefully some exciting developments will follow!
Tom Swift speaks at the Bionow Yorkshire Partnering Event.
031
Thomas Swift @swifthom.bsky.social · 08/04/2025
Jason Jones is presenting at BioNow's Yorkshire biopartnering event - introducing the BDH programme that will follow CAYMAN and SIBLING. £4 million UK funds supporting 100 SME businesses in West Yorkshire- has been great to be part of these schemes working for academic-industry partnerships
010
Thomas Swift @swifthom.bsky.social · 05/04/2025
Meanwhile I've been part of the volunteer team preparing for next week's Rothwell Beer Festival! 40 casks loaded and ready for sale - all profits for charitable causes. Anyone in Leeds region Thursday- Saturday next week get tickets from www.rothwellbeerfestival.co.uk
010
Thomas Swift @swifthom.bsky.social · 05/04/2025
Trying to relax over the weekend and my family have decided to try planting for harvest. Now we have pots of earth squirrels over ever spare cm of indoor space that might catch the light!
010
Thomas Swift @swifthom.bsky.social · 02/04/2025
Grant rejections suck. They particularly suck when the only legible negative part of the feedback is 'There were some concerns about the relevant experience and skills of the proposed team'
100
Thomas Swift @swifthom.bsky.social · 01/04/2025
We got my daughter a Walkie Talkie for Christmas. She loved the concept, but in practice seems to find the idea of people contacting her odd. if anyone calls her through it her go to response to anyone using it is demanding 'what's the matter?' as sternly as she can muster.
000
Thomas Swift @swifthom.bsky.social · 01/04/2025
There's a lot more to say before this story completely wraps up - but right now our focus is on the students and apprentices still with us who we hope to do right by. Senior management team have committed to teaching out all currently enrolled students. www.chemistryworld.com/news/chemist...
chemistryworld.com
Chemistry courses to be shut down at the University of Bradford
Closures are part of a trend seen across UK universities
010
Thomas Swift @swifthom.bsky.social · 31/03/2025
Farewell Swadin Chakraborty, who finishes his 3 month visit from IIT Kharagpur to our labs, going home after a very productive stay. Funded by BBSRC Spark he's kicked off what could be a great larger interdisciplinary collaboration developing new materials
011
Thomas Swift @swifthom.bsky.social · 23/03/2025
Been on a line managers training course for last 6 months that is coming to an end. As part of the final s Reading list just come across a package, written in 2016, that warned about the storm work from home culture would lead to...
100
Thomas Swift @swifthom.bsky.social · 18/03/2025
It's official then! Students were told over a week ago, us a month ago - now the newspapers have picked up on the story. There will be no Chemistry intake at Bradford this September. Am gutted the team has not been able to secure ongoing support. www.timeshighereducation.com/news/bradfor...
timeshighereducation.com
Bradford threatened with strike over job cuts and course closures
Union fears as many as 300 jobs could go at Yorkshire university, plus courses in chemistry and film and television
134
Thomas Swift @swifthom.bsky.social · 17/03/2025
#newmanuscript our collaborators at the University of Leeds have just led newly published work into analysing the interactions of alkylsulfates and keratin in hair using TOF-SIMS analysis. Find the paper online here: aocs.onlinelibrary.wiley.com/doi/10.1002/...
aocs.onlinelibrary.wiley.com
Using time‐of‐flight secondary ion mass spectroscopy to investigate the reaction of alkylsulfate and alkylethoxysulfate surfactants with keratin
Time-of-flight secondary ion mass spectroscopy (ToF-SIMS) was used to investigate the changes in keratin protein surface chemistry caused by the covalent bonding reactions of commercially available a...
000
Thomas Swift @swifthom.bsky.social · 13/03/2025
#newmanuscript Delighted that our analysis of the kinds of steps needed to overcome challenges examining high molar mass polymers using DOSY NMR techniques has been accepted and is available online. Anyone interested can find the early copies here: www.sciencedirect.com/science/arti...
TOC Graphic showing the NMR tracking of solvent Diffusion to determine in solution viscosity of DOSY measurements. Small polymers have minimal impact whilst larger polymers increase viscosity at low concentrations, and demand increased hardware scope to cope with slow diffusion speeds
163
Thomas Swift @swifthom.bsky.social · 07/03/2025
Excellent news to end a rather harrowing week - my 48th peer reviewed scientific article has just been accepted in the Journal of Surfactants and Detergents! Quite a side step compared to what I normally do - heavy on Tim of Flight Secondary Ion Mass Spectroscopy to study biological samples!
Surface profilometry of the materials we were analysing by TOF-SIMS!
Await the paper to find out more!
000
Thomas Swift @swifthom.bsky.social · 04/03/2025
Over on LinkedIn we are celebrating @rsc.org poster competition. Here is my #RSCMat summarising our work on soluble bionanotechnology using highly branched polymers. Delighted to engage and discuss with anyone who wants to know more about the applications of this innovative technology!
020
Thomas Swift @swifthom.bsky.social · 31/01/2025
Delighted to be hosting Swadhin Chakraborty from IIT Kharagpur in our labs in Bradford. He's visiting us for three months to get some experience making branched polymers - am looking forward to some more exciting collaborations!
011
Thomas Swift @swifthom.bsky.social · 07/01/2025
Currently filtering water through a 0.1 micron membrane for light scattering experiments. 18.2 MHz conductivity is not pure enough - we spend hours refining this to ensure there's no trace of dirt whatsoever! #chemsky
161
Thomas Swift @swifthom.bsky.social · 07/01/2025
Happy new year #chemsky. Our research labs are starting back up again, with today's focus the Field Flow Fractionation lamps re-initiated post Christmas shut down. All lights green already - we were worried things would take longer to turn back on!
110
Thomas Swift @swifthom.bsky.social · 13/12/2024
The final 1st year BSc students at @uniofbradford.bsky.social d have ended the semester producing nylon and polystyrene, with festive colours! Have enjoyed overseeing my favourite teaching laboratory experiment to end the year
Nylon with a blue dye being collected in a vesselNylon Web collecting over a glass containerNylon being fed from a vessel containing red dye to produce a strand. We can get meters of material from 1 cup of liquidNylon washing in solution to remove excess HCl
020
Thomas Swift @swifthom.bsky.social · 18/11/2024
A 'lot' of my colleagues and people I recognise from academic communities have turned up here over the last 2 weeks. Welcome! For my own information - but in case anyone finds it useful here are some great polymer scientists. Let me know if I've missed you out: bsky.app/profile/did:...
010
Thomas Swift @swifthom.bsky.social · 18/10/2024
Delighted to announce that a #newpublication has been accepted in the Royal Society of Chemistry: Journal of Materials Chemistry B. Available online - we combine polymer desolvation, branched structures, fluorescent dyes and biological targeting to bind bacteria: pubs.rsc.org/en/content/a...
pubs.rsc.org
Photophysical, Thermal and Imaging Studies on Vancomycin Functional Branched Poly(N-isopropyl acrylamide) of Differing Degrees of Branching Containing Nile Red for Detection of Gram-Positive Bacteria
Highly branched poly(N-isopropyl acrylamide) additives chain end functionalised with vancomycin have been designed to agglutinate and report on targetted Gram-positive strains of bacteria (S. aureus)....
100
Thomas Swift @swifthom.bsky.social · 14/08/2024
Chemists - is anyone in Denver next week? Am there for the ACS meeting Sunday through to Friday and, traveling alone, have no social plans. If anyone is up for a coffee / beer then let me know as I would love to say hi to anyone who can spare an hour!
100
Thomas Swift @swifthom.bsky.social · 10/08/2024
Published in June: New work looking at protein-drug binding via DOSY NMR. A reproducible method to determine accurate binding constants from the change in diffusion speed - a distinct measurement method compared to previous method (proton signal shift). pubs.rsc.org/en/content/a...
pubs.rsc.org
A method for estimation of plasma protein binding using diffusion ordered NMR spectroscopy (DOSY)
The plasma protein binding (PPB) of a drug plays a key role in both its pharmacokinetic and pharmacodynamic properties. During lead optimisation, medium and high throughput methods for the early deter...
162
Thomas Swift @swifthom.bsky.social · 10/08/2024
Published last month! New work in RSC Polymer Chemistry - using DOSY NMR to unpick solution conformation of poly(ethyl oxazoline) and poly(ethylene glycol) in solution. Conformation analysis and ability to predict theta conditions via NMR? Read more here: pubs.rsc.org/en/content/a...
pubs.rsc.org
Polymer conformation determination by NMR spectroscopy: comparative diffusion ordered 1H-NMR spectroscopy of poly(2-ethyl-2-oxazoline)s and poly(ethylene glycol) in D2O
Diffusion ordered 1H-NMR spectroscopy (DOSY) is a useful, non-destructive technique for analysing polymer hydrodynamic size and intrinsic/solution viscosity. However, to date there has been no investi...
013
Thomas Swift @swifthom.bsky.social · 10/08/2024
One really interesting aspect of controlled polymerisation - is that 'functionally' you are dealing with the chemistry of less than 0.1% of the molecule. Yet - subtle incorporation of a chain transfer agent can change everything... #polymerchem
Poly(HEMA) cross linked with EGDMA - with one RAFT chain end visible
010
Thomas Swift @swifthom.bsky.social · 23/05/2024
It's my birthday, and I've written an opinion piece of my Substack Blog about some newspaper stories from last August concerning period products and the downfall of UK Governments. Please feel free to read and share if your interested! open.substack.com/pub/polybiom...
open.substack.com
Periodical Paranoia about Period Products
Half the population needs them - apparently no one of us understand them - and politicians stumble in at their peril
000
Thomas Swift @swifthom.bsky.social · 18/05/2024
Collaborator Amalia Ruiz has just published our work on liposomal AIE-dots for bioimaging and phototherapy in prostate cancer! A really fun collaboration with key international partners available now: www.sciencedirect.com/science/arti...
sciencedirect.com
Oligo(styryl)benzenes liposomal AIE-dots for bioimaging and phototherapy in an in vitro model of prostate cancer
Whilst the development of advanced organic dots with aggregation-induced emission characteristics (AIE-dots) is being intensively studied, their clini…
000
Thomas Swift @swifthom.bsky.social · 10/05/2024
Second MaDADDOSY NMR reaction monitoring of polymerisation work is now published on the journal ACS Polymers Au. This work shows deployment of a bench top NMR to provide DOSY to elucidate molar mass as a polymer reaction proceeds. Read it live here: pubs.acs.org/doi/10.1021/...
pubs.acs.org
Real-Time Determination of Molecular Weight: Use of MaDDOSY (Mass Determination Diffusion Ordered Spectroscopy) to Monitor the Progress of Polymerization Reactions
Knowledge of molecular weight is an integral factor in polymer synthesis, and while many synthetic strategies have been developed to help control this, determination of the final molecular weight is o...
011
Thomas Swift @swifthom.bsky.social · 02/04/2024
Delighted that the first publication from PhD graduate Ali Algadafi is live! This electronic engineering work designed an induction heating coil suitable for studying the thermal response of magnetic nanoparticles for hyperthermia treatment Read full article at: www.mdpi.com/2673-7426/4/2/56
mdpi.com
Design and Modelling of an Induction Heating Coil to Investigate the Thermal Response of Magnetic Nanoparticles for Hyperthermia Applications
Magnetic Field Hyperthermia is a technique where tumours are treated through an increase in local temperature upon exposure to alternating magnetic fields (AMFs) that are mediated by magnetic nano-par...
011
Thomas Swift @swifthom.bsky.social · 14/03/2024
Any Scientists near Leeds with an interest in Polymers or Biomaterials - please consider joining us for a 1 day networking event (free registration) on the 17th of April 2024. A full day of scientific discussions, followed by a beer tasting event put on by Rothwell Beer Festival.
Schedule for the RAPS event in Rothwell, South Leeds, 17th April 2024
100
Thomas Swift @swifthom.bsky.social · 08/03/2024
Just out - a collaboration led by colleague Amalia Ruiz looking at liposomal encapsulation of napthalimides published in RSC Pharmaceutics. My role - chemical analysis and modelling, and using NMR to look at stability of the liposomes and their cargo over days and weeks. doi.org/10.1039/D3PM...
doi.org
Insight into the liposomal encapsulation of mono and bis-naphthalimides
Mitonafide-loaded liposomes are a promising strategy to overcome the neurotoxicity observed in clinical trials for this drug. This study investigates the influence of loaded mitonafide or a dimer anal...
022
Thomas Swift @swifthom.bsky.social · 05/03/2024
I document everything here in a group website I share with one Chemistry Professor and 2 other lecturers. Every paper, discovery, conference or hire gets documented for the record. Find out more by visiting polybiomaterials.com
polybiomaterials.com
Polymer and Biomaterials Chemistry Group
Polymer Biomaterials Research Group - latest news and information about our interdisciplinary team of researchers
000
Thomas Swift @swifthom.bsky.social · 05/03/2024
I also collaborated with a group in Warwick who were working to validate DOSY analysis of polymers on an 80 MHz benchtop NMR - all credit to Owen Tooley and Dan Lester for this work published just at the end of January. More work on DOSY analysis of polymers inbound shortly! doi.org/10.1002/marc...
doi.org
MaDDOSY (Mass Determination Diffusion Ordered Spectroscopy) using an 80 MHz Bench Top NMR for the Rapid Determination of Polymer and Macromolecular Molecular Weight
Macromolecular Rapid Communications, Wiley’s flagship polymers journal, covers chemistry & physics of polymers, and polymers in materials science & life sciences.
122
Thomas Swift @swifthom.bsky.social · 05/03/2024
Might as well share what I'm about. Functional polymer materials - best represented by our big success story published right at the end of 2023! A study of the skin irritancy of silicone v hydrogel adhesives - and how to modify the silicone to improve its breathability pubs.acs.org/doi/10.1021/...
pubs.acs.org
Evaluating the Irritant Factors of Silicone and Hydrocolloid Skin Contact Adhesives Using Trans-Epidermal Water Loss, Protein Stripping, Erythema, and Ease of Removal
A composite silicone skin adhesive material was designed to improve its water vapor permeability to offer advantages to wearer comfort compared to existing skin adhesive dressings available (including...
000
Thomas Swift @swifthom.bsky.social · 05/03/2024
Hi - Polymer Chemistry feed incoming, accounts of an associate professor of a Northern UK University!
031