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Alexey Strygin

@strygah.bsky.social
105 followers 21 following 23 posts

founder, executive, vitalist 🧬 longevity biotech, longevity economics, drug discovery, startups

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Alexey Strygin @strygah.bsky.social · 02/02/2026
Full research, and what would actually move the needle: open.substack.com/pub/strygin/... This is my first Substack post. Subscribe if you want more.
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Alexey Strygin @strygah.bsky.social · 02/02/2026
Full research: open.substack.com/pub/strygin/...
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Alexey Strygin @strygah.bsky.social · 02/02/2026
The funding gap is staggering. 246 billionaires worth $1.56T died of aging this decade. Total ultra-wealthy investment in longevity over 25 years? $5B (according to @wsj.com) The average billionaire who died of aging held more wealth than the entire field's funding.
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Alexey Strygin @strygah.bsky.social · 02/02/2026
After 90, any advantage billionaires have disappears entirely. Billionaire mortality at 90+ is statistically indistinguishable from leading life expectancy countries The Gompertz curve doesn't care about your net worth.
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Alexey Strygin @strygah.bsky.social · 02/02/2026
So how much does being a billionaire buy men? 0-4 extra years beyond the world's healthiest population. Why such a wide range? It's complicated: selection bias, survivor effects, and pre-death wealth loss. Read the full study.
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Alexey Strygin @strygah.bsky.social · 02/02/2026
It sucks to be a female billionaire. Female billionaires die 4.5 years EARLIER than the leading benchmark. The usual 5-7 year female longevity advantage nearly vanishes. Male and female billionaires die at about the same age. No country on Earth shows a gap this small.
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Alexey Strygin @strygah.bsky.social · 02/02/2026
6 helicopter crashes in a decade, in a population of a few thousand. Helicopters are used to compress travel time. For 6 billionaires, they compressed life instead.
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Alexey Strygin @strygah.bsky.social · 02/02/2026
90% of billionaires die of an aging-related disease, or "peacefully," "in their sleep," "surrounded by family." All euphemisms for aging doing what aging does. Caveat: among deaths with known cause. 30% have no publicly disclosed cause (True wealth is quiet)
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Alexey Strygin @strygah.bsky.social · 02/02/2026
I tracked every billionaire who died in the last decade. 389 deaths. $2.17 trillion in wealth. 6 helicopter crashes. Here's what I found.
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Alexey Strygin @strygah.bsky.social · 30/01/2026
Subscribe to get it when it drops: substack.com/@strygah
substack.com
Search "strygah" on Substack
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Alexey Strygin @strygah.bsky.social · 30/01/2026
I'm launching a Substack next week with a piece I've been working on for two months. Original research on billionaire ... (can you guess what?)
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Alexey Strygin @strygah.bsky.social · 14/02/2025
I used to need alcohol as a social lubricant when I was younger. Now I'm the social lubricant myself.
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Alexey Strygin @strygah.bsky.social · 23/12/2024
🚨🚨🚨 Reflections on Zelar.City are out! The organizing team was interviewed during the final days of the 5-week event and daily deep convos We reflect on longevity industry and pop cities A MUST SEE www.youtube.com/watch?v=T5pc...
youtube.com
We build a Longevity Pop-up City - Zelar.city team interview
YouTube video by Elias Schlie (Longevity)
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Alexey Strygin @strygah.bsky.social · 04/12/2024
Is it just me, or am I uncovering new reasons to pursue radical life extension? 🤔 (Of course, we're talking about biological age in theoretical high calendar-year-old 25-year-olds!) Paper for reference: doi.org/10.1101/cshp...
doi.org
International Gains to Achieving Healthy Longevity
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Alexey Strygin @strygah.bsky.social · 04/12/2024
1️⃣ It's way better to be a woman! 2️⃣ If you're a man lucky enough to live to 5,000 years, you're in a world where there are three 25-year-old Japanese women for every one of you! 3️⃣ If you've made it to 10,000 years, the number of women per man is ~7.5.
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Alexey Strygin @strygah.bsky.social · 04/12/2024
3️⃣ We also know there are big differences between male and female mortality rates. I found the mortality rates for 25-year-olds in Japan (0.02% for women, 0.04% for men) and plotted a graph. What do we observe?
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Alexey Strygin @strygah.bsky.social · 04/12/2024
2️⃣ There's a huge variation in lifespan (see the survival curve I modeled): Half the people will die before reaching 1,214.5 years 18% will live up to 3,000 years 5.78% will make it to 5,000 years 0.33% will reach 10,000 years
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Alexey Strygin @strygah.bsky.social · 04/12/2024
1️⃣ Even when we remove aging from the equation, there are still chances of dying (from infections, violence, accidents, and cancers). For 30-year-olds, the mortality rate in the paper is about ~0.057% per year, aligning with data from developed countries like Japan.
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Alexey Strygin @strygah.bsky.social · 04/12/2024
Reversing one year of aging per year essentially hits the Longevity Escape Velocity point. In this scenario, the expected lifespan for 30-year-olds is 1,782.6 years. Way better than now! But there are important nuances (I played around with the data for you): 📊
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Alexey Strygin @strygah.bsky.social · 04/12/2024
I've been digging into Andrew Scott's paper and found an interesting table modeling a theoretical therapy applied once a year that regenerates either 1 year, 9 months, 6 months, or 3 months of aging at different ages (see table). 🧵
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Alexey Strygin @strygah.bsky.social · 29/11/2024
My pronouns are “fuck/death”
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Alexey Strygin @strygah.bsky.social · 25/11/2024
Who is here from longevity biotech?
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Alexey Strygin @strygah.bsky.social · 25/11/2024
How do get banned here? Can I joke?
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