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Sträßer lab

@straesserlab.bsky.social
149 followers 211 following 7 posts

Passionate about uncovering how mRNPs form in the nucleus and how this intertwines with other aspects of gene expression. Based at Justus Liebig University Giessen, Germany. www.uni-giessen.de/de/fbz/fb08/Inst…

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Reposted by Sträßer lab
RTG 2355 @rtg2355.bsky.social · 01/07/2026
Registration is officially closed! 🎉 We are very much looking forward to wonderful speakers, spirited discussions, and plenty of networking. See you this September @jlugiessen.bsky.social !
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Reposted by Sträßer lab
RTG 2355 @rtg2355.bsky.social · 09/06/2026
Deadline alert ⏰⌛- if you want to present a poster or short talk at our conference in September, please submit your abstract by next Sunday, June 14! The template is available for download on the conference website 👉tinyurl.com/rtg2355conf
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Sträßer lab @straesserlab.bsky.social · 05/05/2026
Very happy to host such a line-up of leading #RNA experts @jlugiessen.bsky.social! Come & contribute: tinyurl.com/rtg2355conf
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Reposted by Sträßer lab
Kilchert lab @kilchertlab.bsky.social · 17/04/2026
If after reading the article you are still hungry for more about alternative TREX-2 complexes, also check out the recent preprints from the labs of Torben Heick Jensen @heick.bsky.social and Mary Dasso 😉 www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.6...
biorxiv.org
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Sträßer lab @straesserlab.bsky.social · 26/01/2026
Very happy to share the paper on nuclear mRNA export by Nataliia Stefanyshena now out in #NAR! Nataliia uncovered that, counterintuitively, an excess of the conserved mRNA exporter Mex67 in yeast messenger ribonucleoprotein particles (mRNPs) impairs mRNA export. academic.oup.com/nar/article/...
academic.oup.com
An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA export
Abstract. In eukaryotes, nuclear messenger RNA (mRNA) export is a crucial step in gene expression, mediated by the conserved mRNA exporter Mex67-Mtr2 in Sa
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Reposted by Sträßer lab
RTG 2355 @rtg2355.bsky.social · 26/01/2026
Happy to share the work by Fabienne Becker et al in #NAR, showing how yeast Tho1-CTD stimulates helicase activity of Sub2, homologue of human DDX39B/UAP56, by promoting Sub2 oligomerization on RNA. The scaffolding mechanism is shared across species: academic.oup.com/nar/article/...
academic.oup.com
Tho1 and MOS11 promote nucleic acid double-strand unwinding by facilitating DEAD-box helicase oligomerization
Abstract. DEAD-box helicases are essential for gene expression and RNA metabolism. However, the mechanisms regulating their activity remain largely elusive
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Sträßer lab @straesserlab.bsky.social · 19/12/2025
Proud to bring together so many excellent invited speakers for our RTG 2355 International Conference next September, and looking forward to welcoming you @jlugiessen.bsky.social! 👉 tinyurl.com/rtg2355conf
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Reposted by Sträßer lab
RTG 2355 @rtg2355.bsky.social · 02/07/2025
And here goes another one - @rtg2355.bsky.social-member Fabienne Becker from the Friedhoff lab presented her research at the 2025 Helicase Conference in Lisbon today: "The Conserved C-terminal Domain of Tho1 Stimulates the DEAD-box Helicase Sub2" - more coming soon #proudCoordinator 😉
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Sträßer lab @straesserlab.bsky.social · 02/07/2025
Palina Kot from @straesserlab.bsky.social recently gave a talk on her "Structural and Functional Insights into the Sub2-Yra1-Tho1 Complex in Nuclear mRNP Biogenesis" at the 2nd Polish RNA Biology Meeting in Poznan - #proudPI
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Reposted by Sträßer lab
Julius-Maximilians-Universität Würzburg @uni-wuerzburg.de · 01/07/2025
Congratulations to our biochemistry professor Utz Fischer: he has been elected to @embo.org ! His research focuses on the macromolecular machines of the cell. 📷 Christoph Weiss www.uni-wuerzburg.de/en/news-and-...
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Reposted by Sträßer lab
MPI for Multidisciplinary Sciences @mpi-nat.bsky.social · 15/04/2025
What does it mean to be a woman in science 👩‍🔬? It’s up to you: Join the 9th Women’s Careers and Networks symposium on June 4 and 5 on our Fassberg Campus to explore career opportunities and engage with experts and peers. Learn more about #WoCaNet2025 here 👉 uni-goettingen.de/de/203891.html
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Sträßer lab @straesserlab.bsky.social · 28/05/2025
The two talks were indeed a great start for a great meeting. I am looking forward to more to come!
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Reposted by Sträßer lab
Justus-Liebig-Universität Gießen (JLU) @jlugiessen.bsky.social · 03/03/2025
KI? Aber sicher! Die JLU bietet Studierenden und Beschäftigten mit dem JLU #kiChat ab sofort die datenschutzkonforme Nutzung von #KI-Tools – Werkzeuge in drei verschiedenen Sicherheitsstufen – Keine Preisgabe individueller Nutzerdaten www.uni-giessen.de/de/ueber-uns...
Screenshot der JLU kiChat-Oberfläche.
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Sträßer lab @straesserlab.bsky.social · 28/02/2025
Interested in RNA biology, especially mRNA processing and export from nucleus to cytoplasm? We are looking for an enthusiastic PhD student to investigate the RNA-binding proteins Sub2 and Tho1 🧪🧫🔬 More details and instructions on how to apply: www.uni-giessen.de/de/ueber-uns...
uni-giessen.de
Doctoral student (m/f/d) in the field of RNA Biology
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Sträßer lab @straesserlab.bsky.social · 28/02/2025
We are excited to share the work of Nataliia Stefanyshena who showed that maintenance of an optimal Mex67 level in nuclear mRNPs is required for efficient mRNA export: www.biorxiv.org/content/10.1...
biorxiv.org
An elevated level of the mRNA exporter Mex67-Mtr2 in nuclear mRNPs impairs nuclear mRNA export
In eukaryotes, a crucial step in gene expression is the export of the mRNA out of nucleus. The conserved mRNA exporter Mex67-Mtr2 (NXF1-NXT1 in human) is a key factor in this process. In S. cerevisiae...
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