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Devon Stork

@storkdevon.bsky.social
486 followers 368 following 12 posts

Scientist, synthetic biology. Nonprofit cofounder. I edit microbial genomes and take lots of notes. Writer on the side.

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Devon Stork @storkdevon.bsky.social · 22/11/2024
The part on zero-shot predictions on proteins & RNAs was neat, but doesn't seem revolutionary. They can match other predictive algorithms for fitness of protein/RNA. There's a ceiling on what these models can currently do and they've run into it by using a lot more data. Sure?
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Devon Stork @storkdevon.bsky.social · 22/11/2024
Figure 4E/S8 is exciting. Evo is good at predicting transposon boundaries with entropy, but I bet it encodes more data than that. Why is entropy high at the start of TnpA? What does it look like for bigger operons? Can we use this to explain biological functionality & essentiality at operon-scale?
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