iiinova — where your digital self keeps evolving

Sam Stephens IA @stephenslab.bsky.social · 16/09/2025

I do. I think there are significant modifications to the cell surface previously unrecognized. Hard to be certain where this would lead but I feel it’s start of a new direction with exciting possibilities

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Sam Stephens IA @stephenslab.bsky.social · 05/09/2025

Excited to share a new study from the lab published in Diabetes. This was amazing work performed by Sandra Blom! "Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition" doi.org/10.2337/db25...

doi.org

Proinflammatory Cytokines Mediate Pancreatic β-Cell–Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition

Type 1 diabetes (T1D) is caused by the selective autoimmune ablation of pancreatic β-cells. Emerging evidence reveals β-cell secretory dysfunction arises e

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Sam Stephens IA @stephenslab.bsky.social · 19/04/2025

Thanks to Matt Merrins for helping us upgrade our microscope for perifusion studies @merrinslab.bsky.social

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Sam Stephens IA @stephenslab.bsky.social · 03/04/2025

Check out our recent review describing the bidirectional regulation between the ER and mitochondria www.mdpi.com/3216548

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