Honored to add an opioid chapter to the Lester lab's illustrious "inside-out" pharmacology research! Thanks to Matt Mulcahy, Anand Muthusuamy, Andres Collazo, and Giada Spigolon, and Henry Lester for all their hard work! bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
bpspubs.onlinelibrary.wiley.com
BPS Publications
Opioid receptor antagonists increase the plasma membrane density of μ-opioid receptors (MOR) in vivo, thereby inducing “supersensitivity” to opioid agonists. This phenomenon increases the risk of ove...