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Stem Cell Evidence

@stemcellevidence.bsky.social
160 followers 520 following 333 posts

Curating the evidence in haematopoietic stem cell transplantation. Free monthly Stem Cell Evidence Alert bit.ly/2HMQtb5 @stemcellevidence@fediscience.org #MedSky

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Stem Cell Evidence @stemcellevidence.bsky.social · 7h
🟣New from the #StemCellEvidence alert: ➡️ Interindividual HLA evolutionary divergence in mismatched unrelated donor allo-HCT for malignant hematological disorders by Pagliuca et al. 🔗 Link in the comments #MedSky
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Interindividual HLA evolutionary divergence in mismatched unrelated donor allo-HCT for malignant hematological disorders by Pagliuca et al.
featured in the Stem Cell Evidence Alert - September 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 05/10/2026
🆕From the #StemCellEvidence alert: ➡️Haematopoietic cell transplantation for relapsed or refractory classical Hodgkin lymphoma: a retrospective, registry-based cohort study of 19 498 patients from the EBMT Lymphoma Working Group by Bazarbachi et al. 🔗Link in the comments #MedSky
Image showing a PICO summary for: Haematopoietic cell transplantation for relapsed or refractory classical Hodgkin lymphoma: a retrospective, registry-based cohort study of 19 498 patients from the EBMT Lymphoma Working Group
by Bazarbachi et al.
featured in the Stem Cell Evidence Alert - September 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 02/10/2026
🟣 New from the #StemCellEvidence alert: 📑 Low-dose ruxolitinib for graft-versus-host disease prevention in haploidentical haematopoietic stem-cell transplantation: a multicentre, open-label, randomised, controlled, phase 3 trial by Wu et al. 🔗 Link in the comments #MedSky
Image showing a PICO summary for: Low-dose ruxolitinib for graft-versus-host disease prevention in haploidentical haematopoietic stem-cell transplantation: a multicentre, open-label, randomised, controlled, phase 3 trial
by Wu et al.
featured in the Stem Cell Evidence Alert - September 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 01/10/2026
🆕 From the #StemCellEvidence alert: 📑 Outcomes after 7/8 and <7/8 mismatched unrelated donor PBSC transplantation with PTCy: results from the ACCESS trial by Jimenez Jimenez et al. 🔗 Link in the comments #MedSky
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Outcomes after 7/8 and <7/8 mismatched unrelated donor PBSC transplantation with PTCy: results from the ACCESS trial
by Jimenez Jimenez et al.
featured in the Stem Cell Evidence Alert - September 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 30/09/2026
🟣 New from the #StemCellEvidence alert: 📑 GRIMM-II: A two-stage real-time algorithm for nine-locus HLA imputation and matching with up to three mismatches by Kirshenboim et al. 🔗 Link in the comments #MedSky
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GRIMM-II: A two-stage real-time algorithm for nine-locus HLA imputation and matching with up to three mismatches by Kirshenboim et al.
featured in the Stem Cell Evidence Alert - September 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 29/09/2026
🟣 The #StemCellEvidence alert - September 2026, is out! 🔗 See the link in the comments for the top 10 articles #MedSky
Image showing an extract of the Stem Cell Evidence Alert - September 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 03/09/2026
🟣 New from the #StemCellEvidence alert: 📑 CD19/CD22 bivalent CAR T cells in children, adolescents and young adults with B-ALL: final phase 1 trial results by Silbert et al. 🔗 Link in the comments #MedSky
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CD19/CD22 bivalent CAR T cells in children, adolescents and young adults with B-ALL: final phase 1 trial results 
by Silbert et al.
Link in the comments
featured in the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 03/09/2026
🆕 From the #StemCellEvidence alert: 📑 CMV-specific T-cell receptor-engineered T-cell therapy as first-line treatment for CMV reactivation after haploidentical hematopoietic stem cell transplantation: a phase 2 trial by Tang et al. 🔗 Link in the comments #MedSky
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CMV-specific T-cell receptor-engineered T-cell therapy as first-line treatment for CMV reactivation after haploidentical hematopoietic stem cell transplantation: a phase 2 trial 
by Tang et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 02/09/2026
🟣 New from the #StemCellEvidence alert: 📑 CD19/CD22 bivalent CAR T cells in children, adolescents and young adults with B-ALL: final phase 1 trial results by Silbert et al. 🔗 Link in the comments #MedSky
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CD19/CD22 bivalent CAR T cells in children, adolescents and young adults with B-ALL: final phase 1 trial results 
by Silbert et al.
featured in the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 02/09/2026
🆕 From the #StemCellEvidence alert: 📑 CMV-specific T-cell receptor-engineered T-cell therapy as first-line treatment for CMV reactivation after haploidentical hematopoietic stem cell transplantation: a phase 2 trial by Tang et al. 🔗 Link in the comments #MedSky
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CMV-specific T-cell receptor-engineered T-cell therapy as first-line treatment for CMV reactivation after haploidentical hematopoietic stem cell transplantation: a phase 2 trial 
by Tang et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 01/09/2026
🟣 New from the #StemCellEvidence alert: 📑 Randomized Trial of Two Fractionation Schedules of Myeloablative Busulfan with Fludarabine and Cladribine in Acute Myeloid Leukemia or Myelodysplastic Syndromes by Popat et al. 🔗 Link in the comments #MedSky
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Randomized Trial of Two Fractionation Schedules of Myeloablative Busulfan with Fludarabine and Cladribine in Acute Myeloid Leukemia or Myelodysplastic Syndromes 
by Popat et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 01/09/2026
🆕From the #StemCellEvidence alert: 📑Reduced-Dose Post-Transplant Cyclophosphamide as Graft-Versus-Host Disease Prophylaxis in Matched Donor Allogeneic Stem Cell Transplantation: A #SystematicReview of Efficacy and Toxicity by Shafqat et al. 🔗Link in the comments #MedSky
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Reduced-Dose Post-Transplant Cyclophosphamide as Graft-Versus-Host Disease Prophylaxis in Matched Donor Allogeneic Stem Cell Transplantation: A Systematic Review of Efficacy and Toxicity 
by Shafqat et al.
featured in the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 28/08/2026
🟣 New from the #StemCellEvidence alert: 📑 Incidence, molecular and clinical characteristics of donor-derived hematologic malignancies after allogeneic stem cell transplantation for myeloid malignancies by Perekhrestenko et al. 🔗 Link in the comments #MedSky
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Incidence, molecular and clinical characteristics of donor-derived hematologic malignancies after allogeneic stem cell transplantation for myeloid malignancies 
by Perekhrestenko et al.

featured in the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 28/08/2026
🆕 From the #StemCellEvidence alert: 📑 Chronic GVHD Consortium CATCH Study: Incidence, initial presentation and risk factors for chronic GVHD development by Pidala et al. 🔗 Link in the comments #MedSky
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featured in the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 27/08/2026
🟣 New from the #StemCellEvidence alert: 📑 Donor age as a dual-risk factor for donor safety and recipient survival in allogeneic haematopoietic stem cell transplantation by Nishiwaki et al. 🔗 Link in the comments #MedSky
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Donor age as a dual-risk factor for donor safety and recipient survival in allogeneic haematopoietic stem cell transplantation 
by Nishiwaki et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 27/08/2026
🆕 From the #StemCellEvidence alert: 📑 Evaluation of ex-utero collection for umbilical cord blood banking: A randomized clinical trial comparing cord blood quality with the in-utero technique by Ozbey et al. 🔗 Link in the comments #MedSky
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Evaluation of ex-utero collection for umbilical cord blood banking: A randomized clinical trial comparing cord blood quality with the in-utero technique 
by Ozbey et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 26/08/2026
🟣 New from the #StemCellEvidence alert: 📑 Rituximab Maintenance Added to Ibrutinib-Containing Therapy in Younger, Untreated Patients With Mantle Cell Lymphoma: Results From the TRIANGLE Trial by Ladetto et al. 🔗 Link in the comments #MedSky
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Rituximab Maintenance Added to Ibrutinib-Containing Therapy in Younger, Untreated Patients With Mantle Cell Lymphoma: Results From the TRIANGLE Trial 
by Ladetto et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 26/08/2026
🆕 From the #StemCellEvidence alert: 📑 Comparison of Allo-HSCT outcomes after CAR-T therapy versus chemotherapy in pediatric patients with relapsed/refractory B-ALL: a retrospective study by Li et al. 🔗 Link in the comments #MedSky
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Comparison of Allo-HSCT outcomes after CAR-T therapy versus chemotherapy in pediatric patients with relapsed/refractory B-ALL: a retrospective study 
by Li et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 25/08/2026
📄New from the #StemCellEvidence alert: Donor cell-derived haematological neoplasms after allogeneic haematopoietic cell transplantation: recommendations from the EBMT Practice Harmonisation and Guidelines Committee by Gurnari et al. 🔗Link in the replies #MedSky
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Donor cell-derived haematological neoplasms after allogeneic haematopoietic cell transplantation: recommendations from the EBMT Practice Harmonisation and Guidelines Committee by Gurnari et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 25/08/2026
📄From the #StemCellEvidence alert: High-dose chemotherapy followed by autologous stem-cell transplantation versus non-myeloablative consolidation in primary CNS lymphoma (MATRix/IELSG43): a randomised phase 3 trial by Illerhaus et al. 🔗Link in the replies #MedSky
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High-dose chemotherapy followed by autologous stem-cell transplantation versus non-myeloablative consolidation in primary CNS lymphoma (MATRix/IELSG43): a randomised phase 3 trial by Illerhaus et al.
Featured in the Stem Cell Evidence Alert - August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 24/08/2026
📄 From the #StemCellEvidence alert: The 2024 EBMT activity report: crossing one million HCTs and 20,000 CAR-T. A landmark in cellular therapy by Greco et al. 🔗 Link in the replies #MedSky
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The 2024 EBMT activity report: crossing one million HCTs and 20,000 CAR-T. A landmark in cellular therapy by Greco et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 24/08/2026
📄 New from the #StemCellEvidence alert: Pretransplant Blinatumomab Is Associated With Reduced Relapse and Improved Disease-Free Survival in Adults With B-Cell ALL Undergoing Allogeneic Hematopoietic Cell Transplantation by Ginosyan et al. 🔗 Link in the replies #MedSky
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Pretransplant Blinatumomab Is Associated With Reduced Relapse and Improved Disease-Free Survival in Adults With B-Cell ALL Undergoing Allogeneic Hematopoietic Cell Transplantation by Ginosyan et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 21/08/2026
🟣 New from the #StemCellEvidence alert: 📑 Cellular therapy in mantle cell lymphoma: recommendations from the EBMT practice harmonisation and guidelines committee by Dreger et al. 🔗 Link in the comments #MedSky
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Cellular therapy in mantle cell lymphoma: recommendations from the EBMT practice harmonisation and guidelines committee 
by Dreger et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 21/08/2026
🆕 From the #StemCellEvidence alert: 📑 Significance of CD34+ Cell Dose on Outcomes of Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation in AML: An Analysis Stratified by MRD Status by Gang et al. 🔗Link in the comments #MedSky
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Significance of CD34+ Cell Dose on Outcomes of Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation in AML: An Analysis Stratified by MRD Status 
by Gang et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 20/08/2026
🟣 New from the #StemCellEvidence alert: 📑 Donor-specific transplant outcomes from BMT CTN 1702: a multicenter prospective biologic assignment trial by Bashey et al. 🔗 Link in the comments #MedSky
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Donor-specific transplant outcomes from BMT CTN 1702: a multicenter prospective biologic assignment trial 
by Bashey et al.

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Stem Cell Evidence @stemcellevidence.bsky.social · 20/08/2026
🆕 From the #StemCellEvidence alert: 📑 Better 10-Year Cerebrovascular Outcome After Transplant Than on Standard-Care in Sickle Cell Anemia: DREPAGREFFE Trial by Bernaudin et al. 🔗 Link in the comments #MedSky
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Better 10-Year Cerebrovascular Outcome After Transplant Than on Standard-Care in Sickle Cell Anemia: DREPAGREFFE Trial 
by Bernaudin et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 19/08/2026
✅ New from the #StemCellEvidence alert: 📑 Impact of conditioning regimen on outcomes of young AML patients ( < 40 years) undergoing HCT in complete remission (...) by Maffini et al. 🔗 Link in the comments #MedSky
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Impact of conditioning regimen on outcomes of young AML patients ( < 40 years) undergoing HCT in complete remission, with transplant conditioning intensity score of 3.5-4.0. A study from the acute leukemia working party of the European Society for Blood and Marrow Transplantation 
by Maffini et al.
featured in the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 19/08/2026
🟣 From the #StemCellEvidence alert: 🆕 Infection Burden in Mismatched Unrelated Donor #HematopoieticCellTransplantation: Results from the ACCESS Trial by Auletta et al. 🔗 Link in the comments #MedSky
Image showing a PICO summary for the article:
Infection Burden in Mismatched Unrelated Donor #HematopoieticCellTransplantation: Results from the ACCESS Trial 
by Auletta et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 18/08/2026
🆕 The #StemCellEvidence alert for July/August is out! 🟣 See link in the comments.
Image showing an extract of the Stem Cell Evidence Alert - July/August 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 13/07/2026
🆕 From the #StemCellEvidence alert: 📑 Letermovir prophylaxis timing in standard-risk and very high-risk adult CMV-seropositive allogeneic hematopoietic stem cell transplant recipients: A systematic literature review by Wang et al. 🔗 Link in the comments #MedSky
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Letermovir prophylaxis timing in standard-risk and very high-risk adult CMV-seropositive allogeneic hematopoietic stem cell transplant recipients: A systematic literature review 
by Wang et al.
featured in the Stem Cell Evidence Alert - June 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 10/07/2026
🆕 From the #StemCellEvidence alert: 📑 PTCy-Based versus ATG-Based GVHD Prophylaxis in Mismatched Unrelated Donor HCT: A Secondary Analysis of CIBMTR Data by Rodriguez-Rodriguez et al. 🔗Link in the comments #MedSky
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PTCy-Based versus ATG-Based GVHD Prophylaxis in Mismatched Unrelated Donor HCT: A Secondary Analysis of CIBMTR Data 
by Rodriguez-Rodriguez et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 09/07/2026
🆕 From the #StemCellEvidence alert: 📑 Comparative efficacy and safety of antifungal prophylactic agents in allogeneic hematopoietic stem cell transplantation: A #systematicreview and network #meta-analysis by Li et al. 🔗 Link in the comments
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featured in the Stem Cell Evidence Alert - June 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 08/07/2026
✅ From the #StemCellEvidence alert: 📑 The impact of the cryopreservation period on the CD34+ cell viability of cryopreserved cord blood units by Lee et al. 🔗 Link in the comments #MedSky
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The impact of the cryopreservation period on the CD34+ cell viability of cryopreserved cord blood units 
by Lee et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 07/07/2026
🆕 From the #StemCellEvidence alert: 📑 Cord Blood Transplantation versus Other Donor Sources in High-Risk Acute Myeloid Leukemia by Hirao et al. 🔗Link in the comments #MedSky
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Cord Blood Transplantation versus Other Donor Sources in High-Risk Acute Myeloid Leukemia 
by Hirao et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 06/07/2026
✅From the #StemCellEvidence alert: 📑Impact of post-transplant cyclophosphamide and anti-thymocyte globulin on immune reconstitution in MUD allo-HCT by Furnari et al. 🔗Link in the comments #MedSky
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Impact of post-transplant cyclophosphamide and anti-thymocyte globulin on immune reconstitution in MUD allo-HCT 
by Furnari et al.

featured in the Stem Cell Evidence Alert - June 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 03/07/2026
🆕 From the #StemCellEvidence alert: 📑 A Network #Meta-Analysis of Randomized Trials to Determine Optimal GVHD Prophylaxis in Matched Sibling Donor Transplantation by Bentolila et al. 🔗 Link in the comments #MedSky
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A Network Meta-Analysis of Randomized Trials to Determine Optimal GVHD Prophylaxis in Matched Sibling Donor Transplantation 
by Bentolila et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 02/07/2026
🆕 From the #StemCellEvidence alert: 📑Total body irradiation and smoking interact to increase lung cancer risk after blood or marrow transplantation by Balas et al. 🔗Link in the comments #MedSky
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Total body irradiation and smoking interact to increase lung cancer risk after blood or marrow transplantation 
by Balas et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 01/07/2026
✅ New from the #StemCellEvidence alert: 📑Excellent outcomes using a novel reduced intensity conditioning with thiotepa and post-transplant cyclophosphamide for HLA-matched related donor transplant in adolescents and adults with #sicklecelldisease by Alasbali et al 🔗Link in the comments #MedSky
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Excellent outcomes using a novel reduced intensity conditioning with thiotepa and post-transplant cyclophosphamide for HLA-matched related donor transplant in adolescents and adults with #sicklecelldisease 
by Alasbali et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 30/06/2026
🟣New from the #StemCellEvidence alert: 📑Addition of autologous stem-cell transplantation to an ibrutinib-containing first-line treatment in patients aged 18-65 years with mantle cell lymphoma (TRIANGLE) (...) by Dreyling et al. 🔗Link in the comments #MedSky
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Addition of autologous stem-cell transplantation to an ibrutinib-containing first-line treatment in patients aged 18-65 years with mantle cell lymphoma (TRIANGLE): 4·5-year follow-up of a three-arm, randomised, open-label, phase 3 superiority trial of the European MCL Network 
by Dreyling et al.

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Stem Cell Evidence @stemcellevidence.bsky.social · 29/06/2026
🆕The latest #StemCellEvidence alert is out! 🟣See the top 10 articles in the #StemCell Evidence Alert - June 2026. Each one has an easy-to-read PICO summary. 🔗Link in the comments #MedSky
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Stem Cell Evidence @stemcellevidence.bsky.social · 11/06/2026
New from the #StemCellEvidence alert Eculizumab for Pediatric Hematopoietic Cell Transplant-Associated Thrombotic Microangiopathy: Real-World Response Rates, Predictors of Poor Response, and an Optimal Time Point for Treatment Response Assessment by Schoettler et al. Link in the comments #MedSky
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Eculizumab for Pediatric Hematopoietic Cell Transplant-Associated Thrombotic Microangiopathy: Real-World Response Rates, Predictors of Poor Response, and an Optimal Time Point for Treatment Response Assessment 
by Schoettler et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 10/06/2026
From the #StemCellEvidence alert: Extended HLA Haplotypes and Transplant Survival by Petersdorf et al. Link in the comments #MedSky
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Extended HLA Haplotypes and Transplant Survival 
by Petersdorf et al.
featured in the Stem Cell Evidence Alert - May 2026
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Stem Cell Evidence @stemcellevidence.bsky.social · 09/06/2026
New from the #StemCellEvidence alert: Nonmyeloablative HLA-identical sibling transplant for sickle cell disease in children: A multicenter prospective study by Nickel et al. Link in the comments #MedSky
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Nonmyeloablative HLA-identical sibling transplant for sickle cell disease in children: A multicenter prospective study 
by Nickel et al.

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Stem Cell Evidence @stemcellevidence.bsky.social · 08/06/2026
From the #StemCellEvidence alert: Letermovir improves the outcome of allogenic stem cell transplantation with anti-thymocyte globulin against acute leukemia and myelodysplastic syndromes by Negishi et al. Link in the comments #MedSky
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Letermovir improves the outcome of allogenic stem cell transplantation with anti-thymocyte globulin against acute leukemia and myelodysplastic syndromes 
by Negishi et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 05/06/2026
New from the #StemCellEvidence alert: Haploidentical versus matched unrelated donor transplantation with post-transplant cyclophosphamide: a platform-dependent machine learning analysis of donor age by Mehta et al. Link in the comments
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Haploidentical versus matched unrelated donor transplantation with post-transplant cyclophosphamide: a platform-dependent machine learning analysis of donor age 
by Mehta et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 04/06/2026
From the #StemCellEvidence alert: Safety and efficacy of ciltacabtagene autoleucel for relapsed/refractory multiple myeloma: a CIBMTR study by Hansen et al. 🔗 Link in the comments #MedSky
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Safety and efficacy of ciltacabtagene autoleucel for relapsed/refractory multiple myeloma: a CIBMTR study 
by Hansen et al.

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Stem Cell Evidence @stemcellevidence.bsky.social · 03/06/2026
From the #StemCellEvidence alert: Isatuximab, carfilzomib, lenalidomide and dexamethasone in newly diagnosed multiple myeloma: a randomized phase 3 trial by Gay et al. 🔗Link in the comments #MedSky
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Isatuximab, carfilzomib, lenalidomide and dexamethasone in newly diagnosed multiple myeloma: a randomized phase 3 trial 
by Gay et al.

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Stem Cell Evidence @stemcellevidence.bsky.social · 02/06/2026
New from the #StemCellEvidence alert: Ciprofloxacin prophylaxis in allogeneic haematopoietic cell transplantation reduces bacteraemia but increases antimicrobial resistance without improving patient outcomes by Baltas et al. Link in the comments #MedSky
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Ciprofloxacin prophylaxis in allogeneic haematopoietic cell transplantation reduces bacteraemia but increases antimicrobial resistance without improving patient outcomes 
by Baltas et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 01/06/2026
From the #StemCellEvidence alert: Maintenance Treatment With Gilteritinib Suppresses Post-transplant Relapse in Relapse/Refractory FLT3-Mutated Acute Myeloid Leukemia by Arai et al. Link in the comments #MedSky #StemCellResearch
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Maintenance Treatment With Gilteritinib Suppresses Post-transplant Relapse in Relapse/Refractory FLT3-Mutated Acute Myeloid Leukemia 
by Arai et al.
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Stem Cell Evidence @stemcellevidence.bsky.social · 29/05/2026
New from the #StemCellEvidence alert: Base Editing of HBG1 and HBG2 Promoters for #SickleCellDisease by Gupta et al. Link in the comments #MedSky #StemCellResearch
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Base Editing of HBG1 and HBG2 Promoters for Sickle Cell Disease 
by Gupta et al.
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