Proud to share my last first-author paper.
We report a new clinically relevant model of #breastcancer #brainmetastases and #cancerstemcells as key metastases drivers due to their adaptive interaction with brain cells and vasculature.
Thanks to Giuliana Pelicci’s lab (IEO, Milan) and co-authors.
advanced.onlinelibrary.wiley.com
Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model
This study shows that stem-like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and ...