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Sunny X. Tang, M.D. @stanglab.bsky.social · 13/01/2026

Can we automate clinical assessment of thought disorder by finetuning an #LLM? Come find out at our #ACNP2026 poster this evening (Tue) #12!

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Sunny X. Tang, M.D. @stanglab.bsky.social · 13/01/2026

Shhhhh! I know you're not supposed to choose favorites as a PI, but I might be attending #ACNP2026 with my favorite @stanglab.bsky.social member 🥰🤪🤩.

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Sunny X. Tang, M.D. @stanglab.bsky.social · 07/01/2026

We observed small shifts in defeatist beliefs and self-esteem in the intended directions. More impressively, at 1-week follow-up, the overwhelming majority of participants (90%) reported making progress in at least one of the real-life tasks they had identified... 4/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 07/01/2026

20 participants tried a single session with a researcher, and then were asked to use it on their own for 1 week with no additional incentives. The app was feasible and acceptable with 19 of the 20 participants able to access and willing to use it on their own ... 3/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 07/01/2026

The prototype for NST-SPARK delivers a single session of treatment - eliciting unhelpful beliefs that exacerbate negative symptoms, then providing alternative adaptive beliefs that are reinforced with behavioral experiments carried out via AR... 2/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 09/12/2025

And also distinctive patterns for latency, whereas pause was similar between SSD and depression. 4/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 09/12/2025

And there was a graded effect on number of semantic clusters. But there was a more distinctive pattern for people with schizophrenia spectrum disorders on the size of semantic clusters... 3/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 09/12/2025

We found a graded effect on fluency performance... 2/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 16/09/2025

A negative relationship between Happiness and Thought Disturbance and a positive relationship between Anger and Hostile Suspiciousness were replicated across samples... 3/4

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Sunny X. Tang, M.D. @stanglab.bsky.social · 16/09/2025

A negative relationship between Dominance and Anxious Depression symptoms and a positive relationship between Surprise and Hostile Suspiciousness were replicated across timepoints.... 2/4

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Sunny X. Tang, M.D. @stanglab.bsky.social · 24/07/2025

Super stoked to share that we received the #NOA for our R01!!! We will be using speech and language markers to develop personalized, adaptive markers for #psychosis. Very grateful for the support from the NIMH.

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Sunny X. Tang, M.D. @stanglab.bsky.social · 22/07/2025

🔍 By analyzing both linguistic and paralinguistic speech characteristics, our approach demonstrated robust disorder-specific learning across multiple groups, including those with sub-clinical psychotic experiences & major depressive disorder. 📊 #PrecisionMedicine 3/3

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Sunny X. Tang, M.D. @stanglab.bsky.social · 22/07/2025

The machine learning model achieved 86% accuracy distinguishing conditions on the schizophrenia-bipolar spectrum using speech features. 2/3

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Sunny X. Tang, M.D. @stanglab.bsky.social · 18/06/2025

Examining one feature at-a-time, we can identify quite a few which predict each of the psychosis symptoms domains at a significance level that survives corrections for multiple comparisons. These relationships were largely robust to interactions with gender andrace. 4/6

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Sunny X. Tang, M.D. @stanglab.bsky.social · 18/06/2025

A single component score representing the 357 speech and language features significantly predicted psychosis symptoms over time for all three domains. 3/6

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Sunny X. Tang, M.D. @stanglab.bsky.social · 18/06/2025

We collected 160 sessions for 66 participants x 4 timepoints: 1) around the time of admission, 2) around discharge, 3) and 4) at 3 & 6 month follow up. The final feature set included 357 task-specific features representing a range of speech and language analyses. 2/6

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Sunny X. Tang, M.D. @stanglab.bsky.social · 27/01/2025

Reminder! Submit your abstracts for poster and oral presentations for our DISCOURSE Satellite Meeting by 2/14/25! forms.gle/nW5K9MGtBkqQ...

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Sunny X. Tang, M.D. @stanglab.bsky.social · 06/01/2025

When your mom life and your science skills intersect... and you use your academic poster template to make a science fair poster for your kindergartener...

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Sunny X. Tang, M.D. @stanglab.bsky.social · 10/12/2024

Hey #ACNP2024! Come check out our poster using speech and language features and #MachineLearning for classification in a multi-diagnostic sample. Tuesday #84.

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Sunny X. Tang, M.D. @stanglab.bsky.social · 07/12/2024

North Shore Therapeutics is presenting our preliminary findings suggesting that our AR prototype is promising for targeting negative symptoms in #schizophrenias! Check it out - Poster S11 #TIPS2024.

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Sunny X. Tang, M.D. @stanglab.bsky.social · 07/12/2024

Check out our poster at #TIPS2024 describing our multimodal acoustics and NLP pipeline at the Tang Lab!

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Sunny X. Tang, M.D. @stanglab.bsky.social · 22/11/2024

Several interesting patterns were identified and would be of interest to study in a larger longitudinal study for #NLP markers of psychotherapeutic processes. 4/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 22/11/2024

#NLP features included speech graph representations of 1st-person vs. 2nd/3rd-person pronouns, their centrality, and whether these were used in the context of actively performing actions, or being the object of actions. Also temporal focus and cognitive processes. 3/5

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Sunny X. Tang, M.D. @stanglab.bsky.social · 22/11/2024

Five participants with schizophrenia underwent 24 sessions each of MERIT psychotherapy, which targets metacognition. We explored whether language markers might capture putative changes in participants' expression of their agency, awareness of others, and perspective taking. 2/5

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