Reposted by @soniacruciani.bsky.social
Contributing to this exciting piece of work from the @graeffjohannes.bsky.social lab was a fun ride. We show that partial reprogramming restricted to engram neurons suffices to counteract behavioural, molecular and cellular signs of aging and Alzheimer's. Check it out: www.cell.com/neuron/fullt...
cell.com
Cognitive rejuvenation through partial reprogramming of engram cells
Berdugo-Vega et al. combine partial reprogramming and engram technologies to achieve
molecular rejuvenation of learning-associated neuronal ensembles. Engram reprogramming
counteracts molecular, cellu...
