sonia-longhi.bsky.social @sonia-longhi.bsky.social · 14/09/2026I’m very happy and honoured for having been invited to give a talk at the RTG2467 Summer School on Intrinsically Disordered Proteins (7-11 September, Zbiroh Castle, Czechia). 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 14/09/2026Beyond the fantastic venue, this has been an opportunity to catch out with pioneers in the field such as Vladimir Uversky and Peter Tompa but also to hear about the ongoing scientific projects from very talented PhD students of the RTG 2467 network. 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 14/09/2026A huge thank for this kind invitation to the organizers Andrea Sinz and Oleksandr Sorokin and to Franziska Flesch for the logistics and administrative work. 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 20/07/2026I'm very happy to share this paper of mine just published in Adv Sci. This work is the fruit of years of work and of a very fruitful collaboration with the group of Cyrille Mathieu and of Pierre-Yves Lozach. doi.org/10.1002/advs...doi.orgCysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB SignalingThe cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different type... 100
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 12/05/2026I'm very happy to share this paper of mine just published today. Another compelling example that intrinsically disordered regions (in enzymes) do play a functional role and deserve investigation - instead of being removed prior to enzyme characterization. lnkd.in/dch2PtSylnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 12/05/2026Tamburrini et al. The C-terminal intrinsically disordered region of a fungal lytic polysaccharide monooxygenase binds copper and displays anti-fungal properties. Int J Biol Macromol. 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 12/05/2026Many thanks to all co-authors and a special thank to Ketty Tamburrini, a very talented previous PhD student of mine whom I co-supervised with Jean-Guy Berrin and who was the recipient of a PhD fellowship from the Institut Microbiologie, Bioénergies, Biotechnologie (IM2B) 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 12/05/2026This work was mainly carried out at the Laboratoire AFMB and at the BBF Lab - Biodiversité et Biotechnologie Fongiques Voir moins 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 11/04/2026I'm very happy to share this new paper of mine that is the fruit of the work of Hugo Bost, a very talented PhD student of mine Many thanks to #Agence Innovation Defense and #Aix Marseille University for Hugo's PhD fellowship and to the #ANRS MIE - specific program NIPAH-LISA - for financial support.jbc.org 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 24/12/2025From December the 7th to December the 12th I had the privilege to visit Prof Samrat Mukhopadhyay’s lab at the Indian Institute of Science Education and Research in Mohali, Penjab, India (IISER Mohali; lnkd.in/gwt6C9bt) in the context of our ongoing collaboration financially supported by CEFIPRA. 110
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 01/12/2025I am very glad to announce that today Frank Gondelaud, a previous a post-doc of mine for the past 5 years, has taken up his position as a CNRS Research Engineer, dedicating 50% of his time to my team - "Structural Disorder and Molecular Recognition" - and 50% to the #PBSIM facility at the AFMB lab. 120
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 01/12/2025Je suis très heureuse d’annoncer qu’aujourd’hui Frank Gondelaud, post-doc dans mon équipe depuis 5 ans, prend ses fonctions en tant que Ingénieur de Recherche (IR) CNRS avec affectation 50% à mon équipe “Désordre Structural et Reconnaissance Moléculaire” et 50% à la plateforme #PBSIM à l'AFMB. 100
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 08/10/2025I’m very happy to share this new article of mine that is the result of years of work in the context of a long-standing collaboration with Sara Vaiana (ASU) thanks to the financial support of the National Institutes of Health. A big thank to all co-workers ! rdcu.be/eJ2Gkrdcu.beTransient non-local interactions dominate the dynamics of measles virus NTAILCommunications Chemistry - The measles virus relies on the intrinsically disordered domain of its nucleoprotein, NTAIL, to bind the polymerase complex responsible for viral transcription and... 010
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 16/07/2025A "community" commentary paper on Open Research Europe. Thanks to all contributors! And a special thank to COST ML4NGP COST Action Alexander Miguel Monzon open-research-europe.ec.europa.eu/articles/5-1...open-research-europe.ec.europa.eu 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 19/05/2025Interested to join the AFMB lab to head a new group in computational structural biology? 👉 read this without delay! www.nature.com/naturecareer...nature.comJunior Group Leader Position in Computational Structural Biology - Marseille (Arrondissement), Bouches-du-Rhône (FR) job with AFMB Laboratory (amU/CNRS/INSERM/INRAe) | 12839733Junior Group Leader position with a focus on applying artificial intelligence (AI) to the field of integrative structural biology. 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 02/05/2025Interested to apply for a PhD fellowship? 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 18/03/2025I'm very proud and happy to share our latest paper just published in Protein Science. Many thanks to all contributors - and in particular to Frank Gondelaud - to the #ANR and #FRM for funding, & to the #Eurobiomed competitivity pole for labeling the #ANR #Heniphase project doi.org/10.1002/pro....doi.orgA conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virusThe Hendra (HeV) and Nipah (NiV) viruses are high-priority, biosafety level-4 pathogens that cause fatal neurological and respiratory disease. Their P gene encodes not only the P protein, an essentia... 010
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 13/03/2025www.insmi.cnrs.fr/fr/cnrsinfo/...insmi.cnrs.frKit communication consultation citoyenneN'hésitez pas à partager cette consultation citoyenne à votre entourage grâce au kit de communication. 000
Reposted by @sonia-longhi.bsky.socialSociété Française de Virologie (SFV) @sfvirologie.bsky.social · 24/02/2025Karine Alvarez, Directrice de recherche à l’AFMB, participera aux #JFV2025. Sa présentation portera sur : "La voie d'activation intracellulaire d'un analogue nucléotidique antiviral à large spectre : un outil pour rationaliser la conception de futurs antiviraux." 👩🔬 013
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 23/02/2025Very happy to share this paper of mine on the molecular mechanisms driving the fibrillation of a viral fibrillogenic protein. Many thanks to all my co-workers and in particular to #SamratMukhopadyay (IISER, Mohali, India) and to #CEFIPRA for financial support. doi.org/10.1002/pro....doi.orgUnraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domainHendra virus (HeV) is a biosafety level 4 human pathogen belonging to the Henipavirus genus within the Paramyxoviridae family. In HeV, the phosphoprotein-encoding gene also drives the synthesis of th... 010
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 17/01/2025Extrait de la synthèse de presse du CNRS "HelloQuitteX": des chercheurs français facilitent l'exode des utilisateurs de X www.cnews.fr/vie-numeriqu...cnews.fr«HelloQuitteX» : quelle est cette application créée par des chercheurs français pour partir de X ?Pour permettre aux utilisateurs de quitter plus facilement le réseau social X, détenu par le milliardaire américain Elon Musk, des chercheurs français ont créé une 000
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 15/01/2025Je suis heureuse d’annoncer que le projet collaboratif “STOP1” avec Thierry Desnos (BIAM) a été sélectionné pour financement par l'IM2B (institut-im2b.univ-amu.fr) dans le cadre de l’AAP interdisciplinarité 2024-2025 (institut-im2b.univ-amu.fr/fr/appels-a-...). Un grand merci à l’IM2B!institut-im2b.univ-amu.frInstitut IM2B | Institut Microbiologie, Bioénergies et Biotechnologie (IM2B) 000
Reposted by @sonia-longhi.bsky.socialKresten Lindorff-Larsen @lindorfflarsen.bsky.social · 25/11/2024If you are a PhD student and like protein disorder (or want to learn more), Birthe Kragelund @bbkrage.bsky.social and Kristian Strømgaard are organizing a PhD course on How IDPs work 🧶🧬🧪 Note the cost if you are not at a Danish university. Details: phdcourses.ku.dk/DetailKursus... 16027
sonia-longhi.bsky.social @sonia-longhi.bsky.social · 14/12/2024Very honoured having been invited to give a talk at the 1st symposium on Protein Didorder, Interactions and Dynamics at the #universityofnamur Many thanks to the organisers @CatherineMichaux@JulienMignon @TanguyLeider 000
