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Sodbo Sharapov

@sodbo.bsky.social

17 followers 25 following 1 posts

Statistical geneticist @ Human Technopole

Posts Replies Media

Reposted by Sodbo Sharapov

Nicola Pirastu @npirastu.bsky.social · 21/10/2025

I am very happy to finally share SAFE-LD, a method convert genotypes to an anonymised privacy-preserving version to be used to precisely compute LD. Led by @gdesanctis.bsky.social Claudia Gianbartolomei @sodbo.bsky.social and Davide bolognini. 📄: shorturl.at/BgXqq Github: shorturl.at/b49Wa

biorxiv.org

SAFE-LD: A novel method for the estimation of linkage disequilibrium from summary statistics

Genome-wide association studies (GWAS) have greatly advanced our understanding of the genetic architecture of complex traits. Downstream analyses of GWAS summary statistics require accurate in-sample ...

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Sodbo Sharapov @sodbo.bsky.social · 10/02/2025

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Reposted by Sodbo Sharapov

Jonathan Pritchard @jkpritch.bsky.social · 22/11/2024

In a new preprint led by @TheNikhilMilind, we explored a fascinating paradox: For many traits the number of duplications or loss-of-function (LoF) mutations is correlated with phenotype. Curiously, for most traits, the AVERAGE direction of LoFs and Dups is the SAME. Why?

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Reposted by Sodbo Sharapov

Eric Fauman (he/him) @ericfauman.bsky.social · 25/11/2024

Beats closest gene! @jengreitz.bsky.social @anshulkundaje.bsky.social And others that I can't find on bluesky. But if you're here let me know so I can follow you!

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