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Sinem Saka

@sinemsaka.bsky.social
941 followers 319 following 19 posts

Scientist, Group Leader @EMBL Heidelberg.

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Sinem Saka @sinemsaka.bsky.social · 27/04/2026
Cells are not just bags of molecules. Function depends on spatial interactions: RNAs and/or proteins come together with interaction partners to drive regulation and function. In our new preprint, we introduce ProPER, a novel method for in situ proximity detection. Preprint: tinyurl.com/muju86s6
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Sinem Saka @sinemsaka.bsky.social · 20/03/2026
Spectral multiplexing is typically limited to 4-5 channels. Our new preprint introduces a framework that utilizes DNA barcoding and signal tuning to enable robust spectral unmixing and ground-truth benchmarking to achieve 15-plex subcellular profiling without cycling www.biorxiv.org/content/10.6...
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Sinem Saka @sinemsaka.bsky.social · 01/01/2025
The beautiful DNA-microart created by the wonderful Jennifer Heck and Kristina Jevdokimenko in our group to celebrate the festive season: Using Light-Seq, pixels of a DNA canvas was "painted" on a microscope by photocrosslinking DNA barcodes with 3 different fluorophores @embl.org's PhD course '24
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Sinem Saka @sinemsaka.bsky.social · 13/12/2024
The 1st European Society for Spatial Biology (#ESSB) meeting has been a blast! Great talks, exciting posters, new tech platforms and a budding vibrant community - made this a joy beyond our expectations. See you all again next year's edition at @embl.org Heidelberg on 14-17 Oct 2025!
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