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Simon McGrath @simonmcg.bsky.social · 23/05/2026

Powerful poem about the medical mistreatment of ME/CFS patients, published by The Healing Muse. Written by my friend Veronica Ashenhurst, who has severe ME. Read the whole poem here: (@roberthmcmullen.bsky.social) www.s4me.info/threads/publ...

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Simon McGrath @simonmcg.bsky.social · 12/05/2026

The hi-tech nanopore @nanoporetech.com DNA sequencing method behind the £4.7m study to help crack #Mecfs is simple at heart. 1. Thread a strand of DNA through a tiny hole in a membrane- 2. each DNA letter passing through the pore creates a disticnt signal 3. read off the DNA sequence

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Simon McGrath @simonmcg.bsky.social · 23/04/2026

That would make sense. Also, omicron and later strains were upper respiratory tract infections like common colds. These are generally less severe than lower respiratory tract ones, like pneumonia – and spread better, hence their success.

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Simon McGrath @simonmcg.bsky.social · 15/04/2026

I'd have been waiting as well, and in the end, I decided there was only one way to make sure it happened (extraordinary good luck and a frankly amazing collaboration of people mostly with ME and those close to them. Getting the replication in DecodeME was a big bonus.

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Simon McGrath @simonmcg.bsky.social · 08/08/2025

This powerful poem, Art Therapy, might resonate on #SevereMEDAy. It's by my friend and published poet Veronica Ashenhurst, who grows ever more severe. #Gaslighting Read the whole poem at acropolisjournaluk.wixsite.com/acropolisjou... @tomkindlon.bsky.social @strangerandstranger.net

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Simon McGrath @simonmcg.bsky.social · 06/08/2025

Most of the DNA differences studies are single letters. In the pic above (and here), one person has the letter A, while another has the letter G at the same position. DecodeME looks to see if people with ME have significant differences at these letters compared with controls. Cont...

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Simon McGrath @simonmcg.bsky.social · 06/08/2025

How DecodeME looked for DNA differences: DecodeME was a genome-wide association study (GWAS). Looking at each of 3 billion letters costs too much. So GWAS only in those places where people often have different letters from each other. About 800,000 place for DecodeME. Pic explained below 3/

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Simon McGrath @simonmcg.bsky.social · 06/08/2025

#DecodeME in case you a quick reminder about DNA and how it underpins this study: DNA carries the instructions for how to make and run a human body. It’s effectively a very long string of four different chemicals, named A, T, C and G for short. 1/

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Simon McGrath @simonmcg.bsky.social · 14/11/2024

Figure 2 from the study showing the decline in wages for people diagnosed with #MEcfs

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