Reposted by @sheilafernandzluis.bsky.social
New in @thelancet.com: a 6-country African trial found valganciclovir added to standard care linked to a significant early drop in deaths among infants with severe HIV-associated pneumonia — spotlighting CMV, a long-neglected killer. 🧵 www.thelancet.com/journals/lan...
thelancet.com
Empirical treatment with valganciclovir in infants living with HIV and hospitalised with severe pneumonia in Africa: a multicentre, open-label, factorial, randomised, controlled, superiority trial
Empirical valganciclovir treatment appeared to be associated with a lower hazard of
death in infants with severe HIV-associated pneumonia than SOC alone or SOC plus empirical
tuberculosis treatment, a...